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gtf3c3 general transcription factor IIIC, polypeptide 3 [ Danio rerio (zebrafish) ]

Gene ID: 553318, updated on 9-Dec-2024

Summary

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Official Symbol
gtf3c3provided by ZNC
Official Full Name
general transcription factor IIIC, polypeptide 3provided by ZNC
Primary source
ZFIN:ZDB-GENE-040914-80
See related
Ensembl:ENSDARG00000043247 AllianceGenome:ZFIN:ZDB-GENE-040914-80
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
im:7136784
Summary
Predicted to be involved in transcription by RNA polymerase III. Predicted to be part of transcription factor TFIIIC complex. Orthologous to human GTF3C3 (general transcription factor IIIC subunit 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
human mouse all
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Genomic context

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See gtf3c3 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (6243906..6272146)
105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (5546135..5574535)

Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene reticulophagy regulator family member 2 Neighboring gene FAST kinase domains 2 Neighboring gene malate dehydrogenase 1B, NAD (soluble) Neighboring gene uncharacterized LOC137495397 Neighboring gene HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Chromosomal deletions and inversions mediated by TALENs and CRISPR/Cas in zebrafish. Xiao A, et al. Nucleic Acids Res, 2013 Aug. PMID 23748566, Free PMC Article
  2. Initiation of zebrafish haematopoiesis by the TATA-box-binding protein-related factor Trf3. Hart DO, et al. Nature, 2007 Dec 13. PMID 18046332, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in transcription by RNA polymerase III IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within transcription by RNA polymerase III IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of transcription factor TFIIIC complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
general transcription factor 3C polypeptide 3
Names
general transcription factor IIIC, polypeptide 3, 102kDa

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001256242.1 → NP_001243171.1  general transcription factor 3C polypeptide 3

    Status: PROVISIONAL

    Source sequence(s)
    CABZ01062046, LO017782, LO018629
    UniProtKB/TrEMBL
    A0A8M1P2I0, F1RDA7
    Related
    ENSDARP00000112332.2, ENSDART00000127329.3
    Conserved Domains (4) summary
    smart00028
    Location:844 → 874
    TPR; Tetratricopeptide repeats
    TIGR02552
    Location:445 → 549
    LcrH_SycD; type III secretion low calcium response chaperone LcrH/SycD
    sd00006
    Location:203 → 231
    TPR; TPR repeat [structural motif]
    pfam13414
    Location:238 → 302
    TPR_11; TPR repeat

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007112.7 Reference GRCz11 Primary Assembly

    Range
    6243906..6272146
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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