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setdb1a - SET domain bifurcated histone lysine methyltransferase 1a

Predicted to enable histone H3K9 methyltransferase activity and promoter-specific chromatin binding activity. Predicted to be involved in heterochromatin organization and negative regulation of gene expression. Predicted to act upstream of or within chromatin organization and methylation. Predicted to be located in chromosome. Predicted to be active in nucleus. Is expressed in telencephalon. Human ortholog(s) of this gene implicated in autistic disorder and lung cancer. Orthologous to human SETDB1 (SET domain bifurcated histone lysine methyltransferase 1). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa