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uggt1 UDP-glucose glycoprotein glucosyltransferase 1 [ Danio rerio (zebrafish) ]

Gene ID: 553288, updated on 9-Dec-2024

Summary

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Official Symbol
uggt1provided by ZNC
Official Full Name
UDP-glucose glycoprotein glucosyltransferase 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-061103-619
See related
Ensembl:ENSDARG00000054746 AllianceGenome:ZFIN:ZDB-GENE-061103-619
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:152896
Summary
Predicted to enable UDP-glucose:glycoprotein glucosyltransferase activity and unfolded protein binding activity. Predicted to be involved in ERAD pathway and protein N-linked glycosylation via asparagine. Predicted to act upstream of or within protein glycosylation. Predicted to be located in endoplasmic reticulum lumen. Predicted to be active in endoplasmic reticulum. Orthologous to human UGGT1 (UDP-glucose glycoprotein glucosyltransferase 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
human mouse all
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Genomic context

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See uggt1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
41
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (40830810..40890029, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (40976576..41035817, complement)

Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137488024 Neighboring gene uncharacterized LOC137487481 Neighboring gene heparan sulfate 6-O-sulfotransferase 1a Neighboring gene uncharacterized LOC137488025 Neighboring gene uncharacterized LOC110438100

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables UDP-glucose:glycoprotein glucosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum lumen IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
UDP-glucose:glycoprotein glucosyltransferase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001077534.1 → NP_001071002.1  UDP-glucose:glycoprotein glucosyltransferase 1 precursor

    See identical proteins and their annotated locations for NP_001071002.1

    Status: PROVISIONAL

    Source sequence(s)
    BC125832
    UniProtKB/TrEMBL
    A0A8M9Q922, A0JMD3
    Related
    ENSDARP00000148534.1, ENSDART00000191746.1
    Conserved Domains (2) summary
    cd06432
    Location:1226 → 1473
    GT8_HUGT1_C_like; The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family
    pfam06427
    Location:22 → 1171
    UDP-g_GGTase; UDP-glucose:Glycoprotein Glucosyltransferase

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007113.7 Reference GRCz11 Primary Assembly

    Range
    40830810..40890029 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021480334.2 → XP_021336009.2  UDP-glucose:glycoprotein glucosyltransferase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8M9QEQ5
    Related
    ENSDARP00000107250.3, ENSDART00000123886.3
Nucleotide Protein Strain
Heading Accession and Version

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