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elmod2 ELMO/CED-12 domain containing 2 [ Danio rerio (zebrafish) ]

Gene ID: 553267, updated on 9-Dec-2024

Summary

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Official Symbol
elmod2provided by ZNC
Official Full Name
ELMO/CED-12 domain containing 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-060824-2
See related
Ensembl:ENSDARG00000101669 AllianceGenome:ZFIN:ZDB-GENE-060824-2
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable GTPase activator activity. Predicted to be located in membrane. Orthologous to human ELMOD2 (ELMO domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
human mouse all
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Genomic context

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See elmod2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (53391345..53407463, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (52756607..52772743, complement)

Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene TBC1 domain family, member 9 (with GRAM domain) Neighboring gene uncoupling protein 1 Neighboring gene uncharacterized LOC108190370 Neighboring gene zgc:66455

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Adaptive evolution of the uncoupling protein 1 gene contributed to the acquisition of novel nonshivering thermogenesis in ancestral eutherian mammals. Saito S, et al. Gene, 2008 Jan 31. PMID 18023297
  2. Uncoupling protein 1 in fish uncovers an ancient evolutionary history of mammalian nonshivering thermogenesis. Jastroch M, et al. Physiol Genomics, 2005 Jul 14. PMID 15886331
  3. Exploring uncoupling proteins and antioxidant mechanisms under acute cold exposure in brains of fish. Tseng YC, et al. PLoS One, 2011 Mar 25. PMID 21464954, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ELMO domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001204132.1 → NP_001191061.1  ELMO domain-containing protein 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AL935166
    UniProtKB/TrEMBL
    A0A8M1P1T7, A0A8M3AKQ9
    Related
    ENSDARP00000132763.1, ENSDART00000172322.2
    Conserved Domains (1) summary
    pfam04727
    Location:113 → 267
    ELMO_CED12; ELMO/CED-12 family

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007112.7 Reference GRCz11 Primary Assembly

    Range
    53391345..53407463 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009294631.3 → XP_009292906.1  ELMO domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8M3AKQ9, A0A8M3AT43
    Conserved Domains (1) summary
    pfam04727
    Location:143 → 297
    ELMO_CED12; ELMO/CED-12 family
Nucleotide Protein Strain
Heading Accession and Version

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