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apoa4a apolipoprotein A-IV a [ Danio rerio (zebrafish) ]

Gene ID: 550608, updated on 4-Jan-2025

Summary

Official Symbol
apoa4aprovided by ZNC
Official Full Name
apolipoprotein A-IV aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-050417-469
See related
Ensembl:ENSDARG00000101160 AllianceGenome:ZFIN:ZDB-GENE-050417-469
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:112992
Summary
Predicted to enable lipid binding activity. Predicted to act upstream of or within lipid transport and lipoprotein metabolic process. Predicted to be located in extracellular region. Is expressed in gut; intestine; liver; and yolk syncytial layer. Human ortholog(s) of this gene implicated in Alzheimer's disease; colitis; myocardial infarction; and ulcerative colitis. Orthologous to human APOA4 (apolipoprotein A4). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See apoa4a in Genome Data Viewer
Location:
chromosome: 19
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (10845953..10850834)
105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (10927028..10932136)

Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene lipase, hormone-sensitive a Neighboring gene si:dkey-3n22.9 Neighboring gene uncharacterized LOC137488480 Neighboring gene translocase of outer mitochondrial membrane 40 homolog, like Neighboring gene si:ch73-347e22.4 Neighboring gene apolipoprotein Ea

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables lipid binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within lipid transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within lipoprotein metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001017909.2NP_001017909.2  apolipoprotein A-IV a precursor

    Status: VALIDATED

    Source sequence(s)
    CU855694, FO704833
    UniProtKB/TrEMBL
    A0A8M9P1T6, Q566Q0
    Related
    ENSDARP00000132213.1, ENSDART00000168479.2

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007130.7 Reference GRCz11 Primary Assembly

    Range
    10845953..10850834
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)