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rab3ab RAB3A, member RAS oncogene family, b [ Danio rerio (zebrafish) ]

Gene ID: 550457, updated on 9-Dec-2024

Summary

Official Symbol
rab3abprovided by ZNC
Official Full Name
RAB3A, member RAS oncogene family, bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-041210-268
See related
Ensembl:ENSDARG00000043835 AllianceGenome:ZFIN:ZDB-GENE-041210-268
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
rab3a; zgc:112516; si:ch211-255d18.4
Summary
Predicted to enable GTPase activity and myosin V binding activity. Predicted to be involved in acrosomal vesicle exocytosis; axonogenesis; and synaptic vesicle exocytosis. Predicted to act upstream of or within exocytosis and protein transport. Predicted to be located in several cellular components, including cell projection; lysosome; and postsynapse. Predicted to be active in axon; cytoplasmic vesicle; and plasma membrane. Orthologous to human RAB3A (RAB3A, member RAS oncogene family). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See rab3ab in Genome Data Viewer
Location:
chromosome: 11
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (6819049..6850593)
105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (6809210..6840754)

Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene phosphodiesterase 4C, cAMP-specific b Neighboring gene uncharacterized LOC101886158 Neighboring gene LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated Neighboring gene DEAD (Asp-Glu-Ala-Asp) box polypeptide 49

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 
enables myosin V binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in acrosomal vesicle exocytosis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in axonogenesis IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within exocytosis IEA
Inferred from Electronic Annotation
more info
 
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in synaptic vesicle exocytosis IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in axon IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
is_active_in endosome IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in lysosome IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in postsynapse IEA
Inferred from Electronic Annotation
more info
 
is_active_in synaptic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in synaptic vesicle membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
RAB3A, member RAS oncogene family, b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001017761.1NP_001017761.1  RAB3A, member RAS oncogene family, b

    See identical proteins and their annotated locations for NP_001017761.1

    Status: PROVISIONAL

    Source sequence(s)
    BC093355
    UniProtKB/TrEMBL
    B2GPE8, Q5RGB5
    Related
    ENSDARP00000095064.3, ENSDART00000104289.4
    Conserved Domains (1) summary
    cd01865
    Location:22186
    Rab3; Rab GTPase family 3 contains Rab3A, Rab3B, Rab3C and Rab3D

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007122.7 Reference GRCz11 Primary Assembly

    Range
    6819049..6850593
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)