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Ugt37D1 UDP-glycosyltransferase family 37 member D1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 53511, updated on 9-Dec-2024

Summary

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Official Symbol
Ugt37D1provided by FlyBase
Official Full Name
UDP-glycosyltransferase family 37 member D1provided by FlyBase
Primary source
FLYBASE:FBgn0040260
Locus tag
Dmel_CG17932
See related
AllianceGenome:FB:FBgn0040260
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
AC 005121C; CG17932; Dmel\CG17932; Ugt36Bc; UGT37D1
Summary
Predicted to enable UDP-glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be active in endoplasmic reticulum membrane. Is expressed in several structures, including adult head; anterior endoderm; crystal cell primordium; embryonic/larval midgut primordium; and larval somatic muscle cell. Human ortholog(s) of this gene implicated in several diseases, including alcoholic pancreatitis; bilirubin metabolic disorder (multiple); cholecystolithiasis; cholelithiasis; and female reproductive organ cancer (multiple). Orthologous to several human genes including UGT1A1 (UDP glucuronosyltransferase family 1 member A1); UGT1A10 (UDP glucuronosyltransferase family 1 member A10); and UGT1A3 (UDP glucuronosyltransferase family 1 member A3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See Ugt37D1 in Genome Data Viewer
Location:
36B1-36B1; 2-53 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (16799025..16801584)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (16799025..16801584)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene UDP-glycosyltransferase family 37 member C2 Neighboring gene UDP-glycosyltransferase family 37 member E1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene midway Neighboring gene Chromosome segregation 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Novel TCF-binding sites specify transcriptional repression by Wnt signalling. Blauwkamp TA, et al. EMBO J, 2008 May 21. PMID 18418383, Free PMC Article
  2. Wnt-mediated repression via bipartite DNA recognition by TCF in the Drosophila hematopoietic system. Zhang CU, et al. PLoS Genet, 2014 Aug. PMID 25144371, Free PMC Article
  3. Genome-wide transcription analysis of clinal genetic variation in Drosophila. Chen Y, et al. PLoS One, 2012. PMID 22514645, Free PMC Article
  4. Insect glycobiology: a lectin multigene family in Drosophila melanogaster. Theopold U, et al. Biochem Biophys Res Commun, 1999 Aug 11. PMID 10441526
  5. The UDP-Glycosyltransferase Family in Drosophila melanogaster: Nomenclature Update, Gene Expression and Phylogenetic Analysis. Ahn SJ, et al. Front Physiol, 2021. PMID 33815151, Free PMC Article

See all (36) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables UDP-glycosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables UDP-glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables UDP-glycosyltransferase activity ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in glycosylation ISM
Inferred from Sequence Model
more info
 PubMed 
Component Evidence Code Pubs
is_active_in endoplasmic reticulum membrane ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
UDP-glycosyltransferase family 37 member D1
Names
CG17932-PA
CG17932-PB
CG17932-PC
UDP-glycosyltransferase 36Bc
Ugt36Bc
Ugt37D1-PA
Ugt37D1-PB
Ugt37D1-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    16799025..16801584
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_165193.2 → NP_724013.1  UDP-glycosyltransferase family 37 member D1, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_724013.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SZD9, Q9VJH8
    Related
    FBpp0080469
    Conserved Domains (2) summary
    PHA03392
    Location:25 → 512
    egt; ecdysteroid UDP-glucosyltransferase; Provisional
    pfam00201
    Location:45 → 530
    UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

  2. NM_144370.3 → NP_652627.2  UDP-glycosyltransferase family 37 member D1, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_652627.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SZD9, Q9VJH8
    Related
    FBpp0080468
    Conserved Domains (2) summary
    PHA03392
    Location:25 → 512
    egt; ecdysteroid UDP-glucosyltransferase; Provisional
    pfam00201
    Location:45 → 530
    UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

  3. NM_001299060.1 → NP_001285989.1  UDP-glycosyltransferase family 37 member D1, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285989.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SZD9, Q9VJH8
    Conserved Domains (2) summary
    PHA03392
    Location:25 → 512
    egt; ecdysteroid UDP-glucosyltransferase; Provisional
    pfam00201
    Location:45 → 530
    UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8SZD9 Q8SZD9
Q9VJH8 Q9VJH8

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