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DEFB108A defensin beta 108A [ Homo sapiens (human) ]

Gene ID: 503694, updated on 2-Nov-2024

Summary

Official Symbol
DEFB108Aprovided by HGNC
Official Full Name
defensin beta 108Aprovided by HGNC
Primary source
HGNC:HGNC:18089
See related
AllianceGenome:HGNC:18089
Gene type
pseudo
RefSeq status
INFERRED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
BD-8; DEFB8; hBD-8; DEFB-8; DEFB108; DEFB108B; DEFB108P1
Summary
Predicted to be involved in defense response to bacterium and innate immune response. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See DEFB108A in Genome Data Viewer
Location:
8p23.1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (7934264..7938770, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (12080225..12084735, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (7791786..7796292, complement)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene translation initiation factor IF-2-like Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:7760080-7761002 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:7761003-7761923 Neighboring gene heat shock protein family D (Hsp60) member 1 pseudogene 2 Neighboring gene defensin beta 4A Neighboring gene zinc finger protein 705B Neighboring gene ubiquitin carboxyl-terminal hydrolase 17-like protein 2-like Neighboring gene family with sequence similarity 66 member E Neighboring gene ubiquitin specific peptidase 17 like family member 8

Genomic regions, transcripts, and products

General gene information

Other Names

  • Beta-defensin 108B
  • Beta-defensin 8
  • Defensin, beta 108B
  • defensin beta 108 pseudogene 1

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in defense response to bacterium IEA
Inferred from Electronic Annotation
more info
 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_005426.4 

    Range
    101..4607
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

    Range
    7934264..7938770 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_018654717.1 Reference GRCh38.p14 PATCHES

    Range
    841880..846235 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060932.1 Alternate T2T-CHM13v2.0

    Range
    12080225..12084735 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)