ccdc115 coiled-coil domain containing 115 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ccdc115provided by ZNC
Official Full Name: coiled-coil domain containing 115provided by ZNC
Primary source: ZFIN:ZDB-GENE-050227-20
See related: Ensembl:ENSDARG00000033533 AllianceGenome:ZFIN:ZDB-GENE-050227-20
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:113121
Summary: Predicted to enable unfolded protein binding activity. Predicted to be involved in intracellular iron ion homeostasis. Predicted to act upstream of or within vacuolar proton-transporting V-type ATPase complex assembly. Predicted to be located in endoplasmic reticulum. Predicted to be part of vacuolar proton-transporting V-type ATPase complex. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIo. Orthologous to human CCDC115 (coiled-coil domain containing 115). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 23

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	23	NC_007134.7 (19198244..19201324)
105	previous assembly	GRCz10 (GCF_000002035.5)	23	NC_007134.6 (19264605..19274985)

Chromosome 23 - NC_007134.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables unfolded protein binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in intracellular iron ion homeostasis	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within vacuolar proton-transporting V-type ATPase complex assembly	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in COPI-coated vesicle	IEA Inferred from Electronic Annotation more info
located_in cytoplasmic vesicle	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum	ISS Inferred from Sequence or Structural Similarity more info
located_in endoplasmic reticulum-Golgi intermediate compartment	IEA Inferred from Electronic Annotation more info
located_in endosome	IEA Inferred from Electronic Annotation more info
located_in lysosome	IEA Inferred from Electronic Annotation more info
part_of vacuolar proton-transporting V-type ATPase complex	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: coiled-coil domain-containing protein 115

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.