U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Nplp2 Neuropeptide-like precursor 2 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 50286, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
Nplp2provided by FlyBase
Official Full Name
Neuropeptide-like precursor 2provided by FlyBase
Primary source
FLYBASE:FBgn0287423
Locus tag
Dmel_CG11051
See related
AllianceGenome:FB:FBgn0287423
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:RH08410; CG11051; DIM 7; DIM7; Dmel\CG11051; IM7; NEF; NPLP 2; nplp2; NPLP2
Summary
Involved in humoral immune response. Located in extracellular space. Is expressed in several structures, including adult head; adult heart; amnioserosa; anterior endoderm; and embryonic/larval midgut primordium. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Nplp2 in Genome Data Viewer
Location:
70A6-70A6; 3-40 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (13356376..13357223)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (13349476..13350323)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44559 Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR45886 Neighboring gene uncharacterized protein Neighboring gene SoxNeuro Co-Factor Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The gene "degrees of kevin bacon" (dokb) regulates a social network behaviour in Drosophila melanogaster. Rooke R, et al. Nat Commun, 2024 Apr 30. PMID 38688961, Free PMC Article
  2. The Exchangeable Apolipoprotein Nplp2 Sustains Lipid Flow and Heat Acclimation in Drosophila. Rommelaere S, et al. Cell Rep, 2019 Apr 16. PMID 30995484
  3. Macrophages play a nutritive role in post-metamorphic maturation in Drosophila. Krejčová G, et al. Development, 2024 Apr 1. PMID 38456486
  4. Female-specific myoinhibitory peptide neurons regulate mating receptivity in Drosophila melanogaster. Jang YH, et al. Nat Commun, 2017 Nov 21. PMID 29158481, Free PMC Article
  5. Identification of new immune induced molecules in the haemolymph of Drosophila melanogaster by 2D-nanoLC MS/MS. Verleyen P, et al. J Insect Physiol, 2006 Apr. PMID 16510152

See all (93) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables neuropeptide hormone activity NAS
Non-traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in humoral immune response IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in neuropeptide signaling pathway NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region NAS
Non-traceable Author Statement
more info
 PubMed 
located_in extracellular space IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
Neuropeptide-like precursor 2
Names
CG11051-PA
CG11051-PB
CG11051-PC
NEF peptide
Nplp2-PA
Nplp2-PB
Nplp2-PC
immune induced molecule 7
neuropeptide-like precursor 2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    13356376..13357223
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001300130.1 → NP_001287059.1  Neuropeptide-like precursor 2, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001287059.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VU58
    UniProtKB/TrEMBL
    X2JB24

  2. NM_144173.3 → NP_652430.1  Neuropeptide-like precursor 2, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_652430.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VU58
    UniProtKB/TrEMBL
    X2JB24
    Related
    FBpp0075575

  3. NM_001316458.1 → NP_001303387.1  Neuropeptide-like precursor 2, isoform C [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0S0WH10
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0S0WH10 A0A0S0WH10
Q9VU58.1 Q9VU58
X2JB24 X2JB24

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Chemical Information
Molecular Biology Databases
Research Materials
Tools