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Bclaf3 BCLAF1 and THRAP3 family member 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 501559, updated on 4-Jan-2025

Summary

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Official Symbol
Bclaf3provided by RGD
Official Full Name
BCLAF1 and THRAP3 family member 3provided by RGD
Primary source
RGD:1562161
See related
EnsemblRapid:ENSRNOG00000005135 AllianceGenome:RGD:1562161
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1562161
Summary
Predicted to enable DNA binding activity and transcription coregulator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be part of mediator complex. Orthologous to human BCLAF3 (BCLAF1 and THRAP3 family member 3). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Thymus (RPKM 43.3), Spleen (RPKM 40.8) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Bclaf3 in Genome Data Viewer
Location:
Xq14
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (39065842..39137521, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (35257228..35328883, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (38294009..38353525, complement)

Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene mitogen-activated protein kinase kinase kinase 15 Neighboring gene ubiquitin-like 4A, pseudogene Neighboring gene SH3 domain-containing kinase-binding protein 1 Neighboring gene ribosomal protein S9, pseudogene 13 Neighboring gene MAP7 domain containing 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transcription coregulator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of mediator complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
BCLAF1 and THRAP3 family member 3
Names
uncharacterized protein CXorf23 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001127568.1 → NP_001121040.1  BCLAF1 and THRAP3 family member 3

    See identical proteins and their annotated locations for NP_001121040.1

    Status: PROVISIONAL

    Source sequence(s)
    BC166438
    UniProtKB/TrEMBL
    A6IPM9, B2GUW9, E9PSU1
    Related
    ENSRNOP00000006867.6, ENSRNOT00000006867.8
    Conserved Domains (1) summary
    pfam15440
    Location:3 → 654
    THRAP3_BCLAF1; THRAP3/BCLAF1 family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086039.1 Reference GRCr8

    Range
    39065842..39137521 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039099968.2 → XP_038955896.1  BCLAF1 and THRAP3 family member 3 isoform X1

    UniProtKB/TrEMBL
    A6IPM9, B2GUW9, E9PSU1
    Conserved Domains (1) summary
    pfam15440
    Location:3 → 654
    THRAP3_BCLAF1; THRAP3/BCLAF1 family

  2. XM_039099970.2 → XP_038955898.1  BCLAF1 and THRAP3 family member 3 isoform X2

    UniProtKB/TrEMBL
    A6IPM9
    Conserved Domains (1) summary
    pfam15440
    Location:3 → 653
    THRAP3_BCLAF1; THRAP3/BCLAF1 family

  3. XM_039099972.2 → XP_038955900.1  BCLAF1 and THRAP3 family member 3 isoform X3

    UniProtKB/TrEMBL
    A6IPM9
    Conserved Domains (1) summary
    pfam15440
    Location:3 → 625
    THRAP3_BCLAF1; THRAP3/BCLAF1 family

  4. XM_039099973.2 → XP_038955901.1  BCLAF1 and THRAP3 family member 3 isoform X4

    UniProtKB/TrEMBL
    A0A8I6ASV7, A6IPM9
    Related
    ENSRNOP00000097547.1, ENSRNOT00000114369.2
    Conserved Domains (1) summary
    pfam15440
    Location:3 → 654
    THRAP3_BCLAF1; THRAP3/BCLAF1 family
Nucleotide Protein Strain
Heading Accession and Version

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