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Tmem182 transmembrane protein 182 [ Rattus norvegicus (Norway rat) ]

Gene ID: 501129, updated on 4-Jan-2025

Summary

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Official Symbol
Tmem182provided by RGD
Official Full Name
transmembrane protein 182provided by RGD
Primary source
RGD:1563696
See related
EnsemblRapid:ENSRNOG00000028945 AllianceGenome:RGD:1563696
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1563696
Summary
Predicted to be involved in myotube cell development involved in skeletal muscle regeneration; negative regulation of myoblast differentiation; and negative regulation of myoblast fusion. Predicted to be located in plasma membrane. Orthologous to human TMEM182 (transmembrane protein 182). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Heart (RPKM 857.4), Muscle (RPKM 807.6) and 1 other tissue See more
Orthologs
human mouse all
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Genomic context

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See Tmem182 in Genome Data Viewer
Location:
9q22
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (50555029..50606908)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (43059432..43111318)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (47536824..47588677)

Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103690525 Neighboring gene solute carrier family 9 member A2 Neighboring gene major facilitator superfamily domain containing 9 Neighboring gene uncharacterized LOC120094676 Neighboring gene uncharacterized LOC134480364

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in muscle organ development IEA
Inferred from Electronic Annotation
more info
  
involved_in myotube cell development involved in skeletal muscle regeneration ISO
Inferred from Sequence Orthology
more info
  
involved_in myotube differentiation involved in skeletal muscle regeneration ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of myoblast differentiation ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of myoblast fusion ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
transmembrane protein 182

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109305.1 → NP_001102775.1  transmembrane protein 182

    See identical proteins and their annotated locations for NP_001102775.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473965
    UniProtKB/TrEMBL
    A6INP7
    Related
    ENSRNOP00000049496.5, ENSRNOT00000049349.5
    Conserved Domains (1) summary
    pfam13903
    Location:15 → 220
    Claudin_2; PMP-22/EMP/MP20/Claudin tight junction

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086027.1 Reference GRCr8

    Range
    50555029..50606908
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039084079.1 → XP_038940007.1  transmembrane protein 182 isoform X2

    UniProtKB/TrEMBL
    D3ZZT3
    Conserved Domains (1) summary
    cl21598
    Location:13 → 167
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

  2. XM_039084081.2 → XP_038940009.1  transmembrane protein 182 isoform X4

    Conserved Domains (1) summary
    cl21598
    Location:15 → 110
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

  3. XM_039084077.1 → XP_038940005.1  transmembrane protein 182 isoform X1

    Conserved Domains (1) summary
    cl21598
    Location:15 → 174
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

  4. XM_039084078.2 → XP_038940006.1  transmembrane protein 182 isoform X2

    UniProtKB/TrEMBL
    D3ZZT3
    Conserved Domains (1) summary
    cl21598
    Location:13 → 167
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

  5. XM_039084080.2 → XP_038940008.1  transmembrane protein 182 isoform X3

    Conserved Domains (1) summary
    cl21598
    Location:58 → 121
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family
Nucleotide Protein Strain
Heading Accession and Version

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