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LEW1 Undecaprenyl pyrophosphate synthetase family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 5007686, updated on 18-Sep-2024

Summary

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Official Symbol
LEW1
Official Full Name
Undecaprenyl pyrophosphate synthetase family protein
Primary source
TAIR:AT1G11755
Locus tag
AT1G11755
See related
Araport:AT1G11755
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
LEAF WILTING 1
Summary
Encodes a cis-prenyltransferase, involved in dolichol biosynthesis. Wilted leaves in mutants due to cell membrane lesions. Mutants have increased drought tolerance, but hypersensitve to dark stress.
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Genomic context

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See LEW1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
8
Sequence:
Chromosome: 1; NC_003070.9 (3969681..3971911, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ankyrin repeat family protein Neighboring gene ncRNA Neighboring gene CLP protease proteolytic subunit 6 Neighboring gene mediator of RNA polymerase II transcription subunit-like protein Neighboring gene Plant self-incompatibility protein S1 family

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Dolichol biosynthesis and its effects on the unfolded protein response and abiotic stress resistance in Arabidopsis. Zhang H, et al. Plant Cell, 2008 Jul. PMID 18612099, Free PMC Article
  2. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

General gene information

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NM_001084049.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables dehydrodolichyl diphosphate synthase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within dolichol biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within endoplasmic reticulum unfolded protein response IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within protein N-linked glycosylation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to low light intensity stimulus IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to water deprivation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of dehydrodolichyl diphosphate synthase complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Undecaprenyl pyrophosphate synthetase family protein
NP_001077518.1
  • LEAF WILTING 1 (LEW1); CONTAINS InterPro DOMAIN/s: Di-trans-poly-cis-decaprenylcistransferase-like (InterPro:IPR001441); Has 155 Blast hits to 155 proteins in 74 species: Archae - 0; Bacteria - 0; Metazoa - 62; Fungi - 51; Plants - 42; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    3969681..3971911 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001084049.2 → NP_001077518.1  Undecaprenyl pyrophosphate synthetase family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001077518.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178W879, A0A5S9TXD2, Q8H0V2
Nucleotide Protein
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