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Ino80b INO80 complex subunit B [ Rattus norvegicus (Norway rat) ]

Gene ID: 500225, updated on 27-Nov-2024

Summary

Symbol
Ino80bprovided by RGD
Full Name
INO80 complex subunit Bprovided by RGD
Primary source
RGD:1562258
See related
EnsemblRapid:ENSRNOG00000008873 AllianceGenome:RGD:1562258
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Znhit4; RGD1562258
Summary
Predicted to be involved in several processes, including regulation of embryonic development; regulation of nucleobase-containing compound metabolic process; and telomere maintenance. Predicted to be located in nuclear body and nucleolus. Predicted to be part of Ino80 complex. Orthologous to human INO80B (INO80 complex subunit B). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 101.4), Kidney (RPKM 88.4) and 9 other tissues See more
Orthologs
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Genomic context

See Ino80b in Genome Data Viewer
Location:
4q34
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (117185427..117188930, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (115627907..115631069, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (113954612..113957774, complement)

Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene mannosyl-oligosaccharide glucosidase Neighboring gene WW domain binding protein 1 Neighboring gene uncharacterized LOC108350719 Neighboring gene rhotekin Neighboring gene WD repeat domain 54 Neighboring gene similar to human chromosome 2 open reading frame 81

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in chromatin remodeling ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of DNA repair ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of DNA-templated transcription ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of telomere maintenance in response to DNA damage ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of DNA repair ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of DNA replication ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of DNA strand elongation ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of cell cycle ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of chromosome organization ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of embryonic development ISO
Inferred from Sequence Orthology
more info
 
involved_in telomere maintenance ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of Ino80 complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of Ino80 complex ISO
Inferred from Sequence Orthology
more info
 
located_in nuclear body IEA
Inferred from Electronic Annotation
more info
 
located_in nuclear body ISO
Inferred from Sequence Orthology
more info
 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
INO80 complex subunit B
Names
PAP-1 binding protein
high mobility group AT-hook 1-like 4
zinc finger, HIT type 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001048233.1NP_001041698.1  INO80 complex subunit B

    See identical proteins and their annotated locations for NP_001041698.1

    Status: PROVISIONAL

    Source sequence(s)
    BC105625
    UniProtKB/TrEMBL
    Q0D2L4
    Related
    ENSRNOP00000011921.4, ENSRNOT00000011921.8
    Conserved Domains (2) summary
    pfam04438
    Location:307338
    zf-HIT; HIT zinc finger
    pfam04795
    Location:211291
    PAPA-1; PAPA-1-like conserved region

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086022.1 Reference GRCr8

    Range
    117185427..117188930 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063286523.1XP_063142593.1  INO80 complex subunit B isoform X1