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Rab19 RAB19, member RAS oncogene family [ Rattus norvegicus (Norway rat) ]

Gene ID: 500088, updated on 27-Nov-2024

Summary

Official Symbol
Rab19provided by RGD
Official Full Name
RAB19, member RAS oncogene familyprovided by RGD
Primary source
RGD:1565263
See related
EnsemblRapid:ENSRNOG00000009030 AllianceGenome:RGD:1565263
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable GTPase activity. Predicted to be involved in autophagosome assembly and intracellular protein transport. Predicted to be located in plasma membrane and synaptic vesicle membrane. Predicted to be active in endomembrane system. Orthologous to human RAB19 (RAB19, member RAS oncogene family). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 39.7), Spleen (RPKM 28.9) and 7 other tissues See more
Orthologs
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Genomic context

See Rab19 in Genome Data Viewer
Location:
4q23
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (69123962..69133691)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (68157159..68166889)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (67166412..67176141)

Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene chromatin modifying protein 4B-like 1 Neighboring gene solute carrier family 37, member 3 Neighboring gene small nucleolar RNA SNORA71 Neighboring gene makorin ring finger protein 1 Neighboring gene DENN domain containing 2A

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in autophagosome assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in endomembrane system IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in synaptic vesicle membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001024326.1NP_001019497.1  ras-related protein Rab-19

    See identical proteins and their annotated locations for NP_001019497.1

    Status: PROVISIONAL

    Source sequence(s)
    BC088443
    UniProtKB/Swiss-Prot
    Q5M7U5
    UniProtKB/TrEMBL
    A0A8L2Q5E6, A6IEU7
    Related
    ENSRNOP00000012280.4, ENSRNOT00000012280.7
    Conserved Domains (1) summary
    cd01864
    Location:15179
    Rab19; Rab GTPase family 19 (Rab19)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086022.1 Reference GRCr8

    Range
    69123962..69133691
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)