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Swi5 SWI5 homologous recombination repair protein [ Rattus norvegicus (Norway rat) ]

Gene ID: 499779, updated on 27-Nov-2024

Summary

Official Symbol
Swi5provided by RGD
Official Full Name
SWI5 homologous recombination repair proteinprovided by RGD
Primary source
RGD:1559966
See related
AllianceGenome:RGD:1559966
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in cellular response to ionizing radiation and double-strand break repair via homologous recombination. Predicted to be located in nucleus. Predicted to be part of Swi5-Sfr1 complex and Swi5-Swi2 complex. Orthologous to human SWI5 (SWI5 homologous recombination repair protein). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Testes (RPKM 701.0), Thymus (RPKM 619.8) and 9 other tissues See more
Orthologs
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Genomic context

See Swi5 in Genome Data Viewer
Location:
3p12
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (35972436..35981658, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (15574687..15583760, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (11307981..11317049, complement)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene protein-O-mannosyltransferase 1 Neighboring gene uridine-cytidine kinase 1 Neighboring gene uncharacterized LOC134486071 Neighboring gene golgin A2 Neighboring gene dynamin 1 Neighboring gene U1 spliceosomal RNA

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in DNA repair IEA
Inferred from Electronic Annotation
more info
 
involved_in biological_process ND
No biological Data available
more info
 
involved_in cellular response to ionizing radiation ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to ionizing radiation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in double-strand break repair via homologous recombination IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in double-strand break repair via homologous recombination ISO
Inferred from Sequence Orthology
more info
 
involved_in double-strand break repair via homologous recombination ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
part_of Swi5-Sfr1 complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of Swi5-Sfr1 complex ISO
Inferred from Sequence Orthology
more info
 
part_of Swi5-Sfr1 complex ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
DNA repair protein SWI5 homolog
Names
protein SAE3 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001246661.1NP_001233590.1  DNA repair protein SWI5 homolog

    See identical proteins and their annotated locations for NP_001233590.1

    Status: PROVISIONAL

    Source sequence(s)
    BC082799
    UniProtKB/Swiss-Prot
    Q63ZV7
    UniProtKB/TrEMBL
    A6JU49
    Conserved Domains (1) summary
    pfam07061
    Location:1388
    Swi5

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    35972436..35981658 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063284351.1XP_063140421.1  DNA repair protein SWI5 homolog isoform X1

    UniProtKB/Swiss-Prot
    Q63ZV7
    UniProtKB/TrEMBL
    A6JU49