U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Col24a1 collagen type XXIV alpha 1 chain [ Rattus norvegicus (Norway rat) ]

Gene ID: 499723, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Symbol
Col24a1provided by RGD
Full Name
collagen type XXIV alpha 1 chainprovided by RGD
Primary source
RGD:1565539
See related
EnsemblRapid:ENSRNOG00000014143 AllianceGenome:RGD:1565539
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1565539
Summary
Predicted to be an extracellular matrix structural constituent conferring tensile strength. Predicted to be involved in extracellular matrix organization. Predicted to act upstream of or within hematopoietic progenitor cell differentiation. Predicted to be part of collagen trimer. Predicted to be active in basement membrane and extracellular space. Orthologous to human COL24A1 (collagen type XXIV alpha 1 chain). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Kidney (RPKM 68.3), Muscle (RPKM 19.4) and 5 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Col24a1 in Genome Data Viewer
Location:
2q44
Exon count:
61
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (236872583..237129768)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (234212256..234469445)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (251200686..251436254)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134485995 Neighboring gene outer dense fiber of sperm tails 2-like Neighboring gene uncharacterized LOC134485997 Neighboring gene uncharacterized LOC134485996 Neighboring gene U6 spliceosomal RNA Neighboring gene zinc finger, HIT-type containing 6 Neighboring gene cellular communication network factor 1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7. Nagamachi A, et al. Cancer Cell, 2013 Sep 9. PMID 24029230
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables extracellular matrix structural constituent conferring tensile strength IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in extracellular matrix organization IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within hematopoietic progenitor cell differentiation ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in basement membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of collagen trimer IEA
Inferred from Electronic Annotation
more info
  
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
collagen alpha-1(XXIV) chain; collagen type XXIV alpha 1 chain
Names
collagen, type XXIV, alpha 1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    236872583..237129768
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039103871.2 → XP_038959799.1  collagen alpha-1(XXIV) chain isoform X1

    UniProtKB/TrEMBL
    F1M748
    Related
    ENSRNOP00000106432.1, ENSRNOT00000145229.1
    Conserved Domains (4) summary
    PHA03169
    Location:958 → 1112
    PHA03169; hypothetical protein; Provisional
    pfam01391
    Location:1245 → 1301
    Collagen; Collagen triple helix repeat (20 copies)
    cl02436
    Location:1548 → 1730
    COLFI; Fibrillar collagen C-terminal domain
    cl22861
    Location:41 → 227
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

  2. XM_063282923.1 → XP_063138993.1  collagen alpha-1(XXIV) chain isoform X1

    UniProtKB/TrEMBL
    F1M748
    Related
    ENSRNOP00000102736.1, ENSRNOT00000136098.1

  3. XM_039103872.2 → XP_038959800.1  collagen alpha-1(XXIV) chain isoform X2

    Conserved Domains (3) summary
    PHA03169
    Location:254 → 408
    PHA03169; hypothetical protein; Provisional
    pfam01391
    Location:541 → 597
    Collagen; Collagen triple helix repeat (20 copies)
    cl02436
    Location:844 → 1026
    COLFI; Fibrillar collagen C-terminal domain

RNA

  1. XR_010064497.1 RNA Sequence

  2. XR_010064498.1 RNA Sequence

  3. XR_005501386.2 RNA Sequence

  4. XR_005501387.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools