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Trmt13 tRNA methyltransferase 13 homolog [ Rattus norvegicus (Norway rat) ]

Gene ID: 499697, updated on 9-Dec-2024

Summary

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Official Symbol
Trmt13provided by RGD
Official Full Name
tRNA methyltransferase 13 homologprovided by RGD
Primary source
RGD:1565211
See related
EnsemblRapid:ENSRNOG00000015140 AllianceGenome:RGD:1565211
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Ccdc76
Summary
Predicted to enable tRNA methyltransferase activity. Predicted to be involved in tRNA methylation. Orthologous to human TRMT13 (tRNA methyltransferase 13 homolog). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Biased expression in Heart (RPKM 167.5), Muscle (RPKM 99.7) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Trmt13 in Genome Data Viewer
Location:
2q42
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (207217399..207232467, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (204533630..204547711, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (219615665..219628824, complement)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134485678 Neighboring gene RNA 3'-terminal phosphate cyclase Neighboring gene dihydrolipoamide branched chain transacylase E2 Neighboring gene leucine rich repeat containing 39 Neighboring gene SAS-6 centriolar assembly protein Neighboring gene major facilitator superfamily domain containing 14A Neighboring gene uncharacterized LOC102548510 Neighboring gene solute carrier family 35 member A3 Neighboring gene amylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC124992

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables tRNA 2'-O-methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables tRNA methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in tRNA methylation IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
tRNA:m(4)X modification enzyme TRM13 homolog
Names
coiled-coil domain containing 76
tRNA guanosine-2'-O-methyltransferase TRM13 homolog
NP_001029074.2
XP_038958872.1
XP_038958875.1
XP_038958876.1
XP_038958877.1
XP_038958878.1
XP_038958881.1
XP_063138476.1
XP_063138477.1
XP_063138478.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033902.2 → NP_001029074.2  tRNA:m(4)X modification enzyme TRM13 homolog

    See identical proteins and their annotated locations for NP_001029074.2

    Status: PROVISIONAL

    Source sequence(s)
    BC166503
    UniProtKB/TrEMBL
    A6HVA0, B2GV29, F1MAP3
    Related
    ENSRNOP00000062314.2, ENSRNOT00000064484.5
    Conserved Domains (3) summary
    pfam05206
    Location:165 → 469
    TRM13; Methyltransferase TRM13
    pfam05253
    Location:59 → 80
    zf-U11-48K; U11-48K-like CHHC zinc finger
    pfam11722
    Location:17 → 45
    zf-TRM13_CCCH; CCCH zinc finger in TRM13 protein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    207217399..207232467 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039102948.2 → XP_038958876.1  tRNA:m(4)X modification enzyme TRM13 homolog isoform X3

    Conserved Domains (1) summary
    pfam05206
    Location:24 → 328
    TRM13; Methyltransferase TRM13

  2. XM_039102949.2 → XP_038958877.1  tRNA:m(4)X modification enzyme TRM13 homolog isoform X3

    Conserved Domains (1) summary
    pfam05206
    Location:24 → 328
    TRM13; Methyltransferase TRM13

  3. XM_039102953.2 → XP_038958881.1  tRNA:m(4)X modification enzyme TRM13 homolog isoform X3

    Conserved Domains (1) summary
    pfam05206
    Location:24 → 328
    TRM13; Methyltransferase TRM13

  4. XM_039102947.2 → XP_038958875.1  tRNA:m(4)X modification enzyme TRM13 homolog isoform X3

    Conserved Domains (1) summary
    pfam05206
    Location:24 → 328
    TRM13; Methyltransferase TRM13

  5. XM_039102950.2 → XP_038958878.1  tRNA:m(4)X modification enzyme TRM13 homolog isoform X3

    Conserved Domains (1) summary
    pfam05206
    Location:24 → 328
    TRM13; Methyltransferase TRM13

  6. XM_039102944.2 → XP_038958872.1  tRNA:m(4)X modification enzyme TRM13 homolog isoform X1

    UniProtKB/TrEMBL
    A6HVA0
    Conserved Domains (3) summary
    pfam05206
    Location:165 → 444
    TRM13; Methyltransferase TRM13
    pfam05253
    Location:59 → 80
    zf-U11-48K; U11-48K-like CHHC zinc finger
    pfam11722
    Location:17 → 45
    zf-TRM13_CCCH; CCCH zinc finger in TRM13 protein

  7. XM_063282406.1 → XP_063138476.1  tRNA:m(4)X modification enzyme TRM13 homolog isoform X2

    UniProtKB/TrEMBL
    A6HVA0

  8. XM_063282408.1 → XP_063138478.1  tRNA:m(4)X modification enzyme TRM13 homolog isoform X5

  9. XM_063282407.1 → XP_063138477.1  tRNA:m(4)X modification enzyme TRM13 homolog isoform X4

RNA

  1. XR_010063655.1 RNA Sequence

  2. XR_010063656.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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