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Mfsd4b3 major facilitator superfamily domain containing 4B3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 499463, updated on 14-Jan-2025

Summary

Official Symbol
Mfsd4b3provided by RGD
Official Full Name
major facilitator superfamily domain containing 4B3provided by RGD
Primary source
RGD:1561777
See related
EnsemblRapid:ENSRNOG00000050425 AllianceGenome:RGD:1561777
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Mfsd4b2l2; RGD1561777
Summary
Predicted to enable D-glucose transmembrane transporter activity. Predicted to be involved in hexose transmembrane transport. Predicted to be located in membrane. Orthologous to human MFSD4B (major facilitator superfamily domain containing 4B). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Kidney (RPKM 150.3), Liver (RPKM 127.7) and 4 other tissues See more
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Genomic context

See Mfsd4b3 in Genome Data Viewer
Location:
20q12
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (44923703..44948921, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (43369151..43394397, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (45040743..45054597, complement)

Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120098823 Neighboring gene major facilitator superfamily domain containing 4B2 Neighboring gene Na+ dependent glucose transporter 1 Neighboring gene major facilitator superfamily domain containing 4B2 like 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables D-glucose transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in hexose transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
sodium-dependent glucose transporter 1C
Names
major facilitator superfamily domain containing 4B2 like 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086038.1 Reference GRCr8

    Range
    44923703..44948921 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039099168.2XP_038955096.1  sodium-dependent glucose transporter 1C

    UniProtKB/TrEMBL
    M0RAV5
    Related
    ENSRNOP00000102003.1, ENSRNOT00000155012.1
    Conserved Domains (1) summary
    cl28910
    Location:1398
    MFS; Major Facilitator Superfamily
  2. XM_039099169.2XP_038955097.1  sodium-dependent glucose transporter 1C

    UniProtKB/TrEMBL
    M0RAV5
    Conserved Domains (1) summary
    cl28910
    Location:1398
    MFS; Major Facilitator Superfamily