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Mfsd4b1 major facilitator superfamily domain containing 4B1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 499462, updated on 4-Jan-2025

Summary

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Official Symbol
Mfsd4b1provided by RGD
Official Full Name
major facilitator superfamily domain containing 4B1provided by RGD
Primary source
RGD:1559971
See related
EnsemblRapid:ENSRNOG00000024543 AllianceGenome:RGD:1559971
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Mfsd4b; RGD1559971
Summary
Predicted to enable D-glucose transmembrane transporter activity. Predicted to be involved in hexose transmembrane transport. Predicted to be located in membrane. Orthologous to human MFSD4B (major facilitator superfamily domain containing 4B). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Kidney (RPKM 157.0), Muscle (RPKM 41.1) and 9 other tissues See more
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Genomic context

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See Mfsd4b1 in Genome Data Viewer
Location:
20q12
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (44878985..44888435, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (43324419..43333869, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (44996864..45005155, complement)

Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene U6atac minor spliceosomal RNA Neighboring gene REV3 like, DNA directed polymerase zeta catalytic subunit Neighboring gene peptidylprolyl isomerase G, pseudogene 2 Neighboring gene uncharacterized LOC120098823 Neighboring gene major facilitator superfamily domain containing 4B2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables D-glucose transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in hexose transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
major facilitator superfamily domain containing 4B
Names
sodium-dependent glucose transporter 1C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001402082.1 → NP_001389011.1  major facilitator superfamily domain containing 4B

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000020
    UniProtKB/TrEMBL
    A6KIH2, F1LTM4
    Related
    ENSRNOP00000036588.6, ENSRNOT00000035047.8

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086038.1 Reference GRCr8

    Range
    44878985..44888435 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039099152.2 → XP_038955080.1  major facilitator superfamily domain containing 4B isoform X1

    Conserved Domains (1) summary
    cl28910
    Location:1 → 359
    MFS; Major Facilitator Superfamily
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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