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Mtcp1 mature T-cell proliferation 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 498814, updated on 9-Dec-2024

Summary

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Official Symbol
Mtcp1provided by RGD
Official Full Name
mature T-cell proliferation 1provided by RGD
Primary source
RGD:1561352
See related
EnsemblRapid:ENSRNOG00000056435 AllianceGenome:RGD:1561352
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1561352
Summary
Predicted to enable protein kinase binding activity and protein serine/threonine kinase activator activity. Predicted to be involved in intracellular signal transduction. Orthologous to human MTCP1 (mature T cell proliferation 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Biased expression in Thymus (RPKM 60.9), Spleen (RPKM 35.3) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Mtcp1 in Genome Data Viewer
Location:
18p13
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (142416..144482)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (126189..130123)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (411159..411934, complement)

Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene vomeronasal 2 receptor, 75 Neighboring gene BRCA1/BRCA2-containing complex, subunit 3, pseudogene 7 Neighboring gene FUN14 domain containing 2 Neighboring gene C-X9-C motif containing 4 Neighboring gene uncharacterized LOC134482991 Neighboring gene coagulation factor VIII Neighboring gene myotubularin related protein 1 Neighboring gene uncharacterized LOC134482992

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The protooncogene TCL1 is an Akt kinase coactivator. Laine J, et al. Mol Cell, 2000 Aug. PMID 10983986
  2. Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Mootha VK, et al. Cell, 2003 Nov 26. PMID 14651853
  3. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables protein kinase binding ISO
Inferred from Sequence Orthology
more info
  
enables protein serine/threonine kinase activator activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in intracellular signal transduction ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
protein p13 MTCP-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086036.1 Reference GRCr8

    Range
    142416..144482
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_574098.7 → XP_574098.2  protein p13 MTCP-1

    See identical proteins and their annotated locations for XP_574098.2

    Conserved Domains (1) summary
    pfam01840
    Location:6 → 98
    TCL1_MTCP1; TCL1/MTCP1 family

  2. XM_039097394.2 → XP_038953322.1  protein p13 MTCP-1

    Related
    ENSRNOP00000072400.3, ENSRNOT00000084138.3
    Conserved Domains (1) summary
    pfam01840
    Location:6 → 98
    TCL1_MTCP1; TCL1/MTCP1 family
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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