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Uhmk1l1 U2AF homology motif kinase 1l1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 498754, updated on 14-Nov-2024

Summary

Official Symbol
Uhmk1l1provided by RGD
Official Full Name
U2AF homology motif kinase 1l1provided by RGD
Primary source
RGD:1561897
See related
EnsemblRapid:ENSRNOG00000091174 AllianceGenome:RGD:1561897
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1561897
Summary
Predicted to enable several functions, including ATP binding activity; protein serine/threonine kinase activity; and ribonucleoprotein complex binding activity. Predicted to be involved in several processes, including positive regulation of translational initiation; protein phosphorylation; and regulation of protein export from nucleus. Predicted to be located in axon; neuron projection cytoplasm; and nuclear speck. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See Uhmk1l1 in Genome Data Viewer
Location:
17p11
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (43147379..43149342)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (42241640..42243666, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (44418463..44420729, complement)

Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene TATA-box binding protein associated factor 5 like, pseudogene 2 Neighboring gene serine/threonine-protein kinase Kist-like Neighboring gene transfer RNA serine (anticodon GCU) 9 Neighboring gene H2B clustered histone 9

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables ribonucleoprotein complex binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in neuron projection development IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of translational initiation IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of cell cycle IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of protein export from nucleus IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 
located_in dendrite cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in neuronal ribonucleoprotein granule IEA
Inferred from Electronic Annotation
more info
 
located_in nuclear speck IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
serine/threonine-protein kinase Kist-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086035.1 Reference GRCr8

    Range
    43147379..43149342
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039096185.2XP_038952113.1  serine/threonine-protein kinase Kist-like

    UniProtKB/TrEMBL
    R9PXR8
    Related
    ENSRNOT00000144297.1
    Conserved Domains (2) summary
    cd14020
    Location:46332
    STKc_KIS; Catalytic domain of the Serine/Threonine Kinase, Kinase Interacting with Stathmin (also called U2AF homology motif (UHM) kinase 1)
    cd12465
    Location:342429
    RRM_UHMK1; RNA recognition motif (RRM) found in U2AF homology motif kinase 1 (UHMK1) and similar proteins