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Mcemp1 mast cell-expressed membrane protein 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 498128, updated on 4-Jan-2025

Summary

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Official Symbol
Mcemp1provided by RGD
Official Full Name
mast cell-expressed membrane protein 1provided by RGD
Primary source
RGD:1565374
See related
EnsemblRapid:ENSRNOG00000028259 AllianceGenome:RGD:1565374
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1565374
Summary
Predicted to enable identical protein binding activity. Predicted to be located in membrane. Orthologous to human MCEMP1 (mast cell expressed membrane protein 1). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Lung (RPKM 71.1), Spleen (RPKM 29.2) and 1 other tissue See more
Orthologs
human mouse all
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Genomic context

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See Mcemp1 in Genome Data Viewer
Location:
12p12
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (6519709..6523880)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (1721781..1727350)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (2211970..2217005)

Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene syntaxin binding protein 2 Neighboring gene resistin Neighboring gene foxo1-corepressor-like Neighboring gene trafficking protein particle complex subunit 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Lentiviral-mediated silencing of mast cell-expressed membrane protein 1 promotes angiogenesis of rats with cerebral ischemic stroke. Jian R, et al. J Cell Biochem, 2019 Oct. PMID 31104315

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Lentiviral-mediated silencing of mast cell-expressed membrane protein 1 promotes angiogenesis of rats with cerebral ischemic stroke.
    Title: Lentiviral-mediated silencing of mast cell-expressed membrane protein 1 promotes angiogenesis of rats with cerebral ischemic stroke.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
mast cell-expressed membrane protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001134602.2 → NP_001128074.2  mast cell-expressed membrane protein 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000012
    UniProtKB/TrEMBL
    A6KQ30

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086030.1 Reference GRCr8

    Range
    6519709..6523880
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017598421.3 → XP_017453910.1  mast cell-expressed membrane protein 1 isoform X1

  2. XM_039089664.2 → XP_038945592.1  mast cell-expressed membrane protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A0G2K062, A6KQ30
    Related
    ENSRNOP00000098741.1, ENSRNOT00000139444.1
    Conserved Domains (1) summary
    pfam03954
    Location:91 → 172
    Lectin_N; Hepatic lectin, N-terminal domain

  3. XM_039089666.2 → XP_038945594.1  mast cell-expressed membrane protein 1 isoform X3

    UniProtKB/TrEMBL
    A6KQ30
    Related
    ENSRNOP00000030516.6, ENSRNOT00000031653.6
    Conserved Domains (1) summary
    pfam03954
    Location:81 → 162
    Lectin_N; Hepatic lectin, N-terminal domain
Nucleotide Protein Strain
Heading Accession and Version

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