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Heatr9 HEAT repeat containing 9 [ Rattus norvegicus (Norway rat) ]

Gene ID: 497970, updated on 27-Nov-2024

Summary

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Official Symbol
Heatr9provided by RGD
Official Full Name
HEAT repeat containing 9provided by RGD
Primary source
RGD:1559875
See related
EnsemblRapid:ENSRNOG00000037100 AllianceGenome:RGD:1559875
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1559875
Summary
Predicted to act upstream of or within hematopoietic progenitor cell differentiation. Orthologous to human HEATR9 (HEAT repeat containing 9). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Testes (RPKM 78.5), Spleen (RPKM 8.0) and 2 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Heatr9 in Genome Data Viewer
Location:
10q26
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (68806634..68816815, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (68309128..68320650, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (70726068..70736707, complement)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120095158 Neighboring gene matrix metallopeptidase 28 Neighboring gene TATA-box binding protein associated factor 15 Neighboring gene C-C motif chemokine ligand 5 Neighboring gene C-C motif chemokine ligand 9

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7. Nagamachi A, et al. Cancer Cell, 2013 Sep 9. PMID 24029230

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
acts_upstream_of_or_within hematopoietic progenitor cell differentiation ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
HEAT repeat containing 9; protein HEATR9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001430253.1 → NP_001417182.1  HEAT repeat containing 9 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/TrEMBL
    A0A096MJ97

  2. NM_001430254.1 → NP_001417183.1  HEAT repeat containing 9 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000010

  3. NM_001430255.1 → NP_001417184.1  HEAT repeat containing 9 isoform 3

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000010

  4. NM_001430256.1 → NP_001417185.1  HEAT repeat containing 9 isoform 4

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000010

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    68806634..68816815 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006247018.4 → XP_006247080.1  protein HEATR9 isoform X1

    Related
    ENSRNOP00000068047.1, ENSRNOT00000077035.3
    Conserved Domains (2) summary
    COG1413
    Location:147 → 424
    HEAT; HEAT repeat [General function prediction only]
    pfam13646
    Location:366 → 454
    HEAT_2; HEAT repeats

  2. XM_006247021.4 → XP_006247083.1  protein HEATR9 isoform X4

    Conserved Domains (2) summary
    COG1413
    Location:83 → 306
    HEAT; HEAT repeat [General function prediction only]
    pfam13646
    Location:302 → 390
    HEAT_2; HEAT repeats

  3. XM_063270132.1 → XP_063126202.1  protein HEATR9 isoform X5

  4. XM_063270131.1 → XP_063126201.1  protein HEATR9 isoform X2

  5. XM_006247020.4 → XP_006247082.1  protein HEATR9 isoform X3

    Conserved Domains (1) summary
    pfam13646
    Location:304 → 392
    HEAT_2; HEAT repeats
Nucleotide Protein Strain
Heading Accession and Version

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