mRpL4 mitochondrial ribosomal protein L4 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: mRpL4provided by FlyBase
Official Full Name: mitochondrial ribosomal protein L4provided by FlyBase
Primary source: FLYBASE:FBgn0001995
Locus tag: Dmel_CG5818
See related: AllianceGenome:FB:FBgn0001995
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: BG:DS02740.17; CG5818; Dmel\CG5818; l(2)35Fe; l(2)k14608; l35Fe; L4; mito; mrpL4; Rpl4
Summary: Predicted to be a structural constituent of ribosome. Involved in positive regulation of Notch signaling pathway. Is active in nucleus. Is expressed in adult head. Orthologous to human MRPL4 (mitochondrial ribosomal protein L4). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2L	NT_033779.5 (16328059..16329132, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2L	NT_033779.4 (16328059..16329132, complement)

Chromosome 2L - NT_033779.5 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables structural constituent of ribosome	IBA Inferred from Biological aspect of Ancestor more info
enables structural constituent of ribosome	IEA Inferred from Electronic Annotation more info
enables structural constituent of ribosome	ISS Inferred from Sequence or Structural Similarity more info
enables structural constituent of ribosome	TAS Traceable Author Statement more info	PubMed

Process	Evidence Code	Pubs
involved_in mitochondrial translation	TAS Traceable Author Statement more info	PubMed
involved_in positive regulation of Notch signaling pathway	IGI Inferred from Genetic Interaction more info	PubMed
involved_in translation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of mitochondrial large ribosomal subunit	ISS Inferred from Sequence or Structural Similarity more info
part_of mitochondrial large ribosomal subunit	TAS Traceable Author Statement more info	PubMed
is_active_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in ribosome	IEA Inferred from Electronic Annotation more info

Names: CG5818-PA; lethal(2)35Fe; mRpL4-PA; mitochondrial ribosomal protein large subunit 4

NEW Try the new Transcript table

The following sections contain reference sequences that belong to a specific genome build. Explain