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Mycbpap Mycbp associated protein [ Rattus norvegicus (Norway rat) ]

Gene ID: 494192, updated on 27-Nov-2024

Summary

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Symbol
Mycbpapprovided by RGD
Full Name
Mycbp associated proteinprovided by RGD
Primary source
RGD:1359123
See related
EnsemblRapid:ENSRNOG00000042912 AllianceGenome:RGD:1359123
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
COD106
Summary
Predicted to enable clathrin binding activity and phospholipid binding activity. Involved in chemical synaptic transmission. Predicted to be located in cytoplasm. Predicted to be part of clathrin vesicle coat. Predicted to be active in endosome and plasma membrane. Orthologous to human MYCBPAP (MYCBP associated protein). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Testes (RPKM 99.6), Heart (RPKM 73.6) and 5 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Mycbpap in Genome Data Viewer
Location:
10q26
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (79947200..79967857, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (79450319..79470977, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (82232105..82253649, complement)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene spermatogenesis associated 20 Neighboring gene epsin 3 Neighboring gene uncharacterized LOC108352211 Neighboring gene radical S-adenosyl methionine domain containing 1 Neighboring gene acyl-CoA synthetase family member 2 Neighboring gene chondroadherin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Cod106, a novel synaptic protein expressed in sensory hair cells of the inner ear and in CNS neurons. Reisinger E, et al. Mol Cell Neurosci, 2005 Jan. PMID 15607946
  2. AMAP-1, a novel testis-specific AMY-1-binding protein, is differentially expressed during the course of spermatogenesis. Yukitake H, et al. Biochim Biophys Acta, 2002 Aug 19. PMID 12151104
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables clathrin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phospholipid binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
  
involved_in chemical synaptic transmission IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in spermatogenesis IEA
Inferred from Electronic Annotation
more info
  
involved_in spermatogenesis ISO
Inferred from Sequence Orthology
more info
  
involved_in spermatogenesis ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
part_of clathrin vesicle coat IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in endosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in extrinsic component of plasma membrane TAS
Traceable Author Statement
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
MYCBP-associated protein
Names
cochlea derived protein of 106 kDa
organ of Corti membrane-associated protein of 106 kDa

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001009482.2 → NP_001009482.2  MYCBP-associated protein isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/TrEMBL
    A0A0G2K1H9

  2. NM_001395044.2 → NP_001381973.1  MYCBP-associated protein isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/Swiss-Prot
    Q69CM6, Q69CM7
    Related
    ENSRNOP00000071847.3, ENSRNOT00000086261.3

  3. NM_001415761.1 → NP_001402690.1  MYCBP-associated protein isoform 3

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/TrEMBL
    F1LPD4

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    79947200..79967857 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039086538.2 → XP_038942466.1  MYCBP-associated protein isoform X5

    UniProtKB/TrEMBL
    A0A0G2K1H9
    Conserved Domains (1) summary
    pfam14646
    Location:187 → 602
    MYCBPAP; MYCBP-associated protein family

  2. XM_039086534.2 → XP_038942462.1  MYCBP-associated protein isoform X1

    UniProtKB/Swiss-Prot
    Q69CM6, Q69CM7
    Related
    ENSRNOP00000107004.1, ENSRNOT00000125400.1
    Conserved Domains (1) summary
    pfam14646
    Location:279 → 694
    MYCBPAP; MYCBP-associated protein family

  3. XM_039086536.2 → XP_038942464.1  MYCBP-associated protein isoform X4

    UniProtKB/Swiss-Prot
    Q69CM6, Q69CM7
    Related
    ENSRNOP00000062686.4, ENSRNOT00000066132.5
    Conserved Domains (1) summary
    pfam14646
    Location:195 → 610
    MYCBPAP; MYCBP-associated protein family

  4. XM_063269578.1 → XP_063125648.1  MYCBP-associated protein isoform X2

  5. XM_063269579.1 → XP_063125649.1  MYCBP-associated protein isoform X3

    UniProtKB/TrEMBL
    M0RBQ9
    Related
    ENSRNOP00000067004.2, ENSRNOT00000075795.5

RNA

  1. XR_010055221.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q69CM7.1 GenPept UniProtKB/Swiss-Prot:Q69CM7

Gene LinkOut

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