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cdk2ap2 cyclin dependent kinase 2 associated protein 2 [ Danio rerio (zebrafish) ]

Gene ID: 494160, updated on 9-Dec-2024

Summary

Official Symbol
cdk2ap2provided by ZNC
Official Full Name
cyclin dependent kinase 2 associated protein 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-040718-35
See related
Ensembl:ENSDARG00000103145 AllianceGenome:ZFIN:ZDB-GENE-040718-35
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:92182
Summary
Predicted to enable kinase activity. Predicted to be involved in negative regulation of G1/S transition of mitotic cell cycle and regulation of microtubule cytoskeleton organization. Predicted to act upstream of or within phosphorylation. Predicted to be active in cytoplasm; microtubule; and nucleus. Orthologous to human CDK2AP2 (cyclin dependent kinase 2 associated protein 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See cdk2ap2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (40009874..40015779, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (39291801..39297737, complement)

Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene superoxide dismutase 3, extracellular b Neighboring gene inhibitor of growth family, member 2 Neighboring gene aryl hydrocarbon receptor interacting protein Neighboring gene leucine-rich repeat LGI family, member 2b Neighboring gene coiled-coil domain containing 149b

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in negative regulation of G1/S transition of mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of microtubule cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in microtubule IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
cyclin-dependent kinase 2-associated protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001009898.1NP_001009898.1  cyclin-dependent kinase 2-associated protein 2

    See identical proteins and their annotated locations for NP_001009898.1

    Status: PROVISIONAL

    Source sequence(s)
    BC075917
    UniProtKB/TrEMBL
    A0A0R4IXM4, A0A8M1N3R8, Q6DHQ0
    Related
    ENSDARP00000141347.2, ENSDART00000165373.2
    Conserved Domains (1) summary
    pfam09806
    Location:58110
    CDK2AP; Cyclin-dependent kinase 2-associated protein

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007112.7 Reference GRCz11 Primary Assembly

    Range
    40009874..40015779 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009292801.4XP_009291076.1  cyclin-dependent kinase 2-associated protein 2 isoform X1

    See identical proteins and their annotated locations for XP_009291076.1

    UniProtKB/TrEMBL
    A0A0R4IXM4, A0A8M1N3R8, Q6DHQ0
    Conserved Domains (1) summary
    pfam09806
    Location:58110
    CDK2AP; Cyclin-dependent kinase 2-associated protein

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394500.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    1011..2176 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)