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anxa1c annexin A1c [ Danio rerio (zebrafish) ]

Gene ID: 494158, updated on 4-Jan-2025

Summary

Official Symbol
anxa1cprovided by ZNC
Official Full Name
annexin A1cprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-5274
See related
Ensembl:ENSDARG00000104359 AllianceGenome:ZFIN:ZDB-GENE-030131-5274
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
anx1c; ANX Ic; sb:cb276; zgc:86853; wu:fa22e03; wu:fj17g03; zgc:123146
Summary
Predicted to enable calcium-dependent phospholipid binding activity and phosphatidylserine binding activity. Predicted to be involved in cellular response to glucocorticoid stimulus; phagocytosis; and signal transduction. Predicted to be active in several cellular components, including nucleus; plasma membrane; and vesicle membrane. Is expressed in EVL and periderm. Human ortholog(s) of this gene implicated in brain ischemia and pancreatic cancer. Orthologous to human ANXA1 (annexin A1). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

See anxa1c in Genome Data Viewer
Location:
chromosome: 5
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (65009764..65021736, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (64320767..64332797, complement)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101882342 Neighboring gene annexin A1d Neighboring gene annexin A1b Neighboring gene peptidase, mitochondrial processing subunit alpha

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Clone Names

  • MGC123146

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
enables calcium-dependent phospholipid binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables calcium-dependent phospholipid binding IEA
Inferred from Electronic Annotation
more info
 
enables phosphatidylserine binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in cellular response to glucocorticoid stimulus IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in phagocytosis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in vesicle membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
annexin A1c
Names
annexin 1c

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_181760.2NP_861425.1  annexin A1c

    See identical proteins and their annotated locations for NP_861425.1

    Status: PROVISIONAL

    Source sequence(s)
    AY178795
    UniProtKB/TrEMBL
    A0A8M1PAK9, Q804H0
    Related
    ENSDARP00000139017.1, ENSDART00000166183.2
    Conserved Domains (1) summary
    pfam00191
    Location:272337
    Annexin; Annexin

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    65009764..65021736 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005165606.5XP_005165663.1  annexin A1c isoform X1

    See identical proteins and their annotated locations for XP_005165663.1

    UniProtKB/TrEMBL
    A0A8M1PAK9, Q804H0
    Related
    ENSDARP00000137943.1, ENSDART00000162368.2
    Conserved Domains (1) summary
    pfam00191
    Location:272337
    Annexin; Annexin