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pcdh2ab10 protocadherin 2 alpha b 10 [ Danio rerio (zebrafish) ]

Gene ID: 493598, updated on 9-Dec-2024

Summary

Official Symbol
pcdh2ab10provided by ZNC
Official Full Name
protocadherin 2 alpha b 10provided by ZNC
Primary source
ZFIN:ZDB-GENE-041118-9
See related
Ensembl:ENSDARG00000103906 AllianceGenome:ZFIN:ZDB-GENE-041118-9
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zcnrv10
Summary
Predicted to enable calcium ion binding activity. Predicted to be involved in cell adhesion. Predicted to act upstream of or within homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to several human genes including PCDHA1 (protocadherin alpha 1); PCDHA10 (protocadherin alpha 10); and PCDHA12 (protocadherin alpha 12). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See pcdh2ab10 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (2123123..2193248, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (2204772..2274797, complement)

Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene protocadherin 2 gamma 12 Neighboring gene protocadherin 2 gamma 10 Neighboring gene protocadherin 2 gamma 13 Neighboring gene protocadherin 2 gamma 9 Neighboring gene protocadherin 2 gamma 8 Neighboring gene protocadherin 2 gamma 7 Neighboring gene protocadherin 2 gamma 6 Neighboring gene protocadherin 2 gamma 5 Neighboring gene protocadherin 2 gamma 2 Neighboring gene protocadherin 2 gamma 1 Neighboring gene protocadherin beta-15 Neighboring gene protocadherin 2 gamma 3 Neighboring gene protocadherin 2 alpha b 12 Neighboring gene protocadherin 2 alpha a 15 Neighboring gene protocadherin 2 alpha b 11 Neighboring gene protocadherin 2 alpha b 9 Neighboring gene protocadherin 2 alpha b 8 Neighboring gene protocadherin 2 alpha b 5 Neighboring gene protocadherin 2 alpha b 3 Neighboring gene protocadherin 2 alpha b2 Neighboring gene protocadherin 2 alpha b 1 Neighboring gene protocadherin 2 alpha a 3 Neighboring gene protocadherin 2 alpha a 1 Neighboring gene protocadherin 2 alpha c Neighboring gene protocadherin alpha-3-like Neighboring gene protocadherin gamma-A4-like

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within cell adhesion IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within homophilic cell adhesion via plasma membrane adhesion molecules IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protocadherin 2 alpha b 10
Names
cadherin-related neuronal receptor variable 10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001009589.2NP_001009589.2  protocadherin 2 alpha b 10 precursor

    Status: VALIDATED

    Source sequence(s)
    CR847851, CT573264
    UniProtKB/TrEMBL
    Q60I67
    Related
    ENSDARP00000110062.2, ENSDART00000128659.3
    Conserved Domains (4) summary
    cd11304
    Location:245344
    Cadherin_repeat; Cadherin tandem repeat domain
    pfam08266
    Location:28109
    Cadherin_2; Cadherin-like
    pfam15974
    Location:795912
    Cadherin_tail; Cadherin C-terminal cytoplasmic tail, catenin-binding region
    pfam16492
    Location:686758
    Cadherin_C_2; Cadherin cytoplasmic C-terminal

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007125.7 Reference GRCz11 Primary Assembly

    Range
    2123123..2193248 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)