bin2a bridging integrator 2a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: bin2aprovided by ZNC
Official Full Name: bridging integrator 2aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-041114-126
See related: Ensembl:ENSDARG00000003219 AllianceGenome:ZFIN:ZDB-GENE-041114-126
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: bin2; wu:fb62b04; zgc:101542
Summary: Predicted to enable phospholipid binding activity. Predicted to be involved in phagocytosis, engulfment; plasma membrane tubulation; and podosome assembly. Predicted to be located in cytoplasm. Predicted to be active in plasma membrane and podosome. Predicted to colocalize with phagocytic cup. Orthologous to human BIN2 (bridging integrator 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 23

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	23	NC_007134.7 (33739215..33753394, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	23	NC_007134.6 (33812684..33827033, complement)

Chromosome 23 - NC_007134.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables phospholipid binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in phagocytosis, engulfment	IBA Inferred from Biological aspect of Ancestor more info
involved_in plasma membrane tubulation	IBA Inferred from Biological aspect of Ancestor more info
involved_in podosome assembly	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
colocalizes_with phagocytic cup	IBA Inferred from Biological aspect of Ancestor more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in podosome	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: bridging integrator 2a

Names: bridging integrator 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.