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ftsj1 FtsJ RNA 2'-O-methyltransferase 1 [ Danio rerio (zebrafish) ]

Gene ID: 492512, updated on 9-Dec-2024

Summary

Official Symbol
ftsj1provided by ZNC
Official Full Name
FtsJ RNA 2'-O-methyltransferase 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-041114-83
See related
Ensembl:ENSDARG00000057089 AllianceGenome:ZFIN:ZDB-GENE-041114-83
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fb17g12; wu:fb17g12; zgc:101831
Summary
Predicted to enable tRNA methyltransferase activity. Predicted to be involved in cytoplasmic translation and tRNA methylation. Predicted to act upstream of or within RNA methylation and tRNA processing. Predicted to be active in cytoplasm. Is expressed in cerebellum and heart. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 9. Orthologous to human FTSJ1 (FtsJ RNA 2'-O-methyltransferase 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See ftsj1 in Genome Data Viewer
Location:
chromosome: 21
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (21170611..21178751, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (21133975..21142272, complement)

Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137488803 Neighboring gene uncharacterized LOC103909452 Neighboring gene RPTOR independent companion of MTOR, complex 2b Neighboring gene LIF receptor subunit alpha b

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Clone Names

  • MGC174324

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables tRNA methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables tRNA methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within RNA methylation IEA
Inferred from Electronic Annotation
more info
 
involved_in cytoplasmic translation IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within methylation IEA
Inferred from Electronic Annotation
more info
 
involved_in tRNA methylation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in tRNA nucleoside ribose methylation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within tRNA processing IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase
Names
FtsJ RNA methyltransferase homolog 1
FtsJ homolog 1
NP_001007385.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001007384.2NP_001007385.2  tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase

    See identical proteins and their annotated locations for NP_001007385.2

    Status: VALIDATED

    Source sequence(s)
    BC085449, BC153564, CN024934, EH566274
    UniProtKB/TrEMBL
    A0A0R4IQE6, A0A8M1N3G9, A8E5E3, F1QDU3
    Related
    ENSDARP00000074130.5, ENSDART00000079678.7
    Conserved Domains (1) summary
    COG0293
    Location:5206
    RlmE; 23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ [Translation, ribosomal structure and biogenesis]

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007132.7 Reference GRCz11 Primary Assembly

    Range
    21170611..21178751 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018395089.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    351919..359994 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)