U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

GstD3 Glutathione S transferase D3 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 48336, updated on 9-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
GstD3provided by FlyBase
Official Full Name
Glutathione S transferase D3provided by FlyBase
Primary source
FLYBASE:FBgn0010039
Locus tag
Dmel_CG4381
See related
AllianceGenome:FB:FBgn0010039
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:LP11313; CG4381; D3; Dmel\CG4381; DmGST22; DmGSTD3; gst; Gst; GST-D3; gstD22; GstD22; gstd3; gstD3; GSTD3
Summary
Predicted to be involved in glutathione metabolic process. Predicted to be located in cytoplasm. Is expressed in several structures, including adult head; anterior endoderm; embryonic/larval midgut primordium; gut section; and posterior endoderm. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See GstD3 in Genome Data Viewer
Location:
87B8-87B8; 3-52 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (12373068..12373813)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (8198790..8199535)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR46015 Neighboring gene Glutathione S transferase D2 Neighboring gene Glutathione S transferase D4 Neighboring gene Glutathione S transferase D5

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. PARTICIPATION OF Y89 AND Y97 IN THE CONJUGATING ACTIVITY OF Drosophila melanogaster GLUTATHIONE S-TRANSFERASE D3 (DmGSTD3). Vignesvaran K, et al. Arch Insect Biochem Physiol, 2016 Jul. PMID 27075600
  2. Behavioral and Transcriptional Response to Selection for Olfactory Behavior in Drosophila. Brown EB, et al. G3 (Bethesda), 2020 Apr 9. PMID 32024668, Free PMC Article
  3. The glutathione S-transferase D genes. A divergently organized, intronless gene family in Drosophila melanogaster. Toung YP, et al. J Biol Chem, 1993 May 5. PMID 7683659
  4. Identification of methylmercury tolerance gene candidates in Drosophila. Mahapatra CT, et al. Toxicol Sci, 2010 Jul. PMID 20375079, Free PMC Article
  5. Antimicrobial peptides increase tolerance to oxidant stress in Drosophila melanogaster. Zhao HW, et al. J Biol Chem, 2011 Feb 25. PMID 21148307, Free PMC Article

See all (67) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
NOT enables glutathione transferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in glutathione metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

Go to the top of the page Help
Preferred Names
glutathione S transferase D3
Names
CG4381-PA
Glutathione-S-transferase D3
GstD3-PA
glutathione S transferase D22

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    12373068..12373813
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_176479.2 → NP_788656.1  glutathione S transferase D3 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_788656.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8MT68, Q9VG97
    Related
    FBpp0082042
    Conserved Domains (3) summary
    cd03177
    Location:72 → 188
    GST_C_Delta_Epsilon; C-terminal, alpha helical domain of Class Delta and Epsilon Glutathione S-transferases
    COG0625
    Location:6 → 173
    GstA; Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]
    cd03045
    Location:1 → 58
    GST_N_Delta_Epsilon; GST_N family, Class Delta and Epsilon subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
AAB26513.1
Q9VG97.1 Q9VG97

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools