U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Eip63F-1 Ecdysone-induced protein 63F 1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 47878, updated on 9-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
Eip63F-1provided by FlyBase
Official Full Name
Ecdysone-induced protein 63F 1provided by FlyBase
Primary source
FLYBASE:FBgn0004910
Locus tag
Dmel_CG15855
See related
AllianceGenome:FB:FBgn0004910
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
63F-1; Ca[2+] binding protein; CBP12; CG15855; Dmel\CG15855; E63-1; E63F; Eip63-1; eip63F-1; Eip63F1; Eip63Fa
Summary
Enables calcium ion binding activity. Predicted to be involved in microtubule cytoskeleton organization. Located in cytoplasm; nucleus; and plasma membrane. Is expressed in several structures, including embryonic/larval fat body; embryonic/larval midgut; embryonic/larval salivary gland; ganglia; and imaginal disc. Orthologous to human CALML5 (calmodulin like 5). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Eip63F-1 in Genome Data Viewer
Location:
63F6-64A1; 3-9 cM
Exon count:
11
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (3909973..3935617, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (3909973..3935617, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene imaginal discs arrested Neighboring gene maggie Neighboring gene antisense RNA:Ecdysone-induced gene 63F 2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The Drosophila 63F early puff contains E63-1, an ecdysone-inducible gene that encodes a novel Ca(2+)-binding protein. Andres AJ, et al. Development, 1995 Aug. PMID 7671827
  2. Ecdysone signaling cascade and regulation of Drosophila metamorphosis. Baehrecke EH. Arch Insect Biochem Physiol, 1996. PMID 8913033
  3. Drosophila ecdysone receptor mutations reveal functional differences among receptor isoforms. Bender M, et al. Cell, 1997 Dec 12. PMID 9413987
  4. Glue secretion in the Drosophila salivary gland: a model for steroid-regulated exocytosis. Biyasheva A, et al. Dev Biol, 2001 Mar 1. PMID 11180965
  5. Roles for RNA export factor, Nxt1, in ensuring muscle integrity and normal RNA expression in Drosophila. van der Graaf K, et al. G3 (Bethesda), 2021 Jan 18. PMID 33561245, Free PMC Article

See all (43) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables calcium ion binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables calcium ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables enzyme regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in microtubule cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
Ecdysone-induced protein 63F 1
Names
CG15855-PA
CG15855-PB
CG15855-PC
CG15855-PD
Eip63F-1-PA
Eip63F-1-PB
Eip63F-1-PC
Eip63F-1-PD

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    3909973..3935617 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001202116.1 → NP_001189045.1  Ecdysone-induced protein 63F 1, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001189045.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9MSK2
    Conserved Domains (1) summary
    PTZ00184
    Location:11 → 161
    PTZ00184; calmodulin; Provisional

  2. NM_001202118.2 → NP_001189047.1  Ecdysone-induced protein 63F 1, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001189047.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9MS04
    Conserved Domains (1) summary
    PTZ00184
    Location:9 → 166
    PTZ00184; calmodulin; Provisional

  3. NM_001202117.2 → NP_001189046.1  Ecdysone-induced protein 63F 1, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001189046.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9MRP5
    Conserved Domains (1) summary
    PTZ00184
    Location:21 → 181
    PTZ00184; calmodulin; Provisional

  4. NM_080163.4 → NP_524902.2  Ecdysone-induced protein 63F 1, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524902.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P48593, Q9I7T4, Q9VZL0
    UniProtKB/TrEMBL
    C6SUU8
    Related
    FBpp0073031
    Conserved Domains (1) summary
    PTZ00184
    Location:33 → 193
    PTZ00184; calmodulin; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9MRP5 M9MRP5
M9MS04 M9MS04
M9MSK2 M9MSK2
P48593.2 P48593
Q95TC2 Q95TC2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools