dpf2 double PHD fingers 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: dpf2provided by ZNC
Official Full Name: double PHD fingers 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-041024-2
See related: Ensembl:ENSDARG00000012219 AllianceGenome:ZFIN:ZDB-GENE-041024-2
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: im:7146797; zgc:101789
Summary: Predicted to enable metal ion binding activity. Predicted to be involved in nervous system development. Predicted to be located in nucleus. Predicted to be part of nBAF complex. Is expressed in brain; epiphysis; and spinal cord. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 7. Orthologous to human DPF2 (double PHD fingers 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	5	NC_007116.7 (37744635..37759853)
105	previous assembly	GRCz10 (GCF_000002035.5)	5	NC_007116.6 (37144459..37159551)

Chromosome 5 - NC_007116.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: zinc finger protein ubi-d4

Names: D4, zinc and double PHD fingers family 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001007152.1 → NP_001007153.1 zinc finger protein ubi-d4

See identical proteins and their annotated locations for NP_001007153.1

Status: PROVISIONAL

Source sequence(s)

BC083281

UniProtKB/TrEMBL

Q5XJL8

Related

ENSDARP00000003264.9, ENSDART00000014031.11

Conserved Domains (3) summary

cd15530
Location:336 → 381

PHD2_d4; PHD finger 2 found in d4 gene family proteins

cd15691
Location:279 → 334

PHD1_DPF2_like; PHD finger 1 found in D4, zinc and double PHD fingers family 2 (DPF2)

pfam14051
Location:13 → 77

Requiem_N; N-terminal domain of DPF2/REQ

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007116.7 Reference GRCz11 Primary Assembly

Range

37744635..37759853

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005165302.5 → XP_005165359.1 zinc finger protein ubi-d4 isoform X1

UniProtKB/TrEMBL

A0A8M2BCR7

Conserved Domains (3) summary

cd15530
Location:350 → 395

PHD2_d4; PHD finger 2 found in d4 gene family proteins

cd15691
Location:293 → 348

PHD1_DPF2_like; PHD finger 1 found in D4, zinc and double PHD fingers family 2 (DPF2)

pfam14051
Location:13 → 77

Requiem_N; N-terminal domain of DPF2/REQ
XM_009301640.4 → XP_009299915.1 zinc finger protein ubi-d4 isoform X2

UniProtKB/TrEMBL

A0A8M3B9T0

Conserved Domains (3) summary

cd15530
Location:346 → 391

PHD2_d4; PHD finger 2 found in d4 gene family proteins

cd15691
Location:289 → 344

PHD1_DPF2_like; PHD finger 1 found in D4, zinc and double PHD fingers family 2 (DPF2)

pfam14051
Location:9 → 73

Requiem_N; N-terminal domain of DPF2/REQ