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SrpRbeta Signal recognition particle receptor beta [ Drosophila melanogaster (fruit fly) ]

Gene ID: 47283, updated on 9-Dec-2024

Summary

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Official Symbol
SrpRbetaprovided by FlyBase
Official Full Name
Signal recognition particle receptor betaprovided by FlyBase
Primary source
FLYBASE:FBgn0011509
Locus tag
Dmel_CG33162
See related
AllianceGenome:FB:FBgn0011509
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:GM04779; CG33162; CG5950; Dm SRbeta; Dmel\CG33162; l(3)rK561; l(3)rL537; Q9VSN9; SRbeta; srpRbeta
Summary
Predicted to enable signal recognition particle binding activity. Involved in chitin-based larval cuticle pattern formation. Located in endomembrane system. Is expressed in adult head and eye-antennal disc. Orthologous to human SRPRB (SRP receptor subunit beta). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See SrpRbeta in Genome Data Viewer
Location:
66D11-66D11; 3-26 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (8718949..8720225, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (8712049..8713325, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene hairy Neighboring gene long non-coding RNA:CR44526 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Construction and transposition of a 100-kilobase extended P element in Drosophila. Ring BC, et al. Genome Res, 2000 Oct. PMID 11042158, Free PMC Article
  2. Nascent polypeptide-Associated Complex and Signal Recognition Particle have cardiac-specific roles in heart development and remodeling. Schroeder AM, et al. PLoS Genet, 2022 Oct. PMID 36240221, Free PMC Article
  3. Small GTPases and the evolution of the eukaryotic cell. Jékely G. Bioessays, 2003 Nov. PMID 14579253
  4. A genetic screen in Drosophila reveals novel cytoprotective functions of the autophagy-lysosome pathway. Arsham AM, et al. PLoS One, 2009 Jun 29. PMID 19562034, Free PMC Article
  5. Gene amplification as a developmental strategy: isolation of two developmental amplicons in Drosophila. Claycomb JM, et al. Dev Cell, 2004 Jan. PMID 14723854

See all (46) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity TAS
Traceable Author Statement
more info
 PubMed 
enables signal recognition particle binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in chitin-based larval cuticle pattern formation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in larval chitin-based cuticle development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein targeting to ER IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein targeting to ER ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in endomembrane system HDA PubMed 
located_in endoplasmic reticulum membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
part_of signal recognition particle receptor complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of signal recognition particle receptor complex ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
signal recognition particle receptor beta
Names
CG33162-PA
CG33162-PB
SrpRbeta-PA
SrpRbeta-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    8718949..8720225 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001274667.1 → NP_001261596.1  signal recognition particle receptor beta, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001261596.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q6IDG2, Q9U4F7, Q9VSN9
    Conserved Domains (2) summary
    cd04105
    Location:49 → 243
    SR_beta; Signal recognition particle receptor, beta subunit (SR-beta), together with SR-alpha, forms the heterodimeric signal recognition particle (SRP)
    pfam09439
    Location:51 → 221
    SRPRB; Signal recognition particle receptor beta subunit

  2. NM_176307.3 → NP_788485.1  signal recognition particle receptor beta, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_788485.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q6IDG2, Q9U4F7, Q9VSN9
    Related
    FBpp0076325
    Conserved Domains (2) summary
    cd04105
    Location:49 → 243
    SR_beta; Signal recognition particle receptor, beta subunit (SR-beta), together with SR-alpha, forms the heterodimeric signal recognition particle (SRP)
    pfam09439
    Location:51 → 221
    SRPRB; Signal recognition particle receptor beta subunit
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VSN9 Q9VSN9

Gene LinkOut

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