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l(3)05822 lethal (3) 05822 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 47260, updated on 9-Dec-2024

Summary

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Official Symbol
l(3)05822provided by FlyBase
Official Full Name
lethal (3) 05822provided by FlyBase
Primary source
FLYBASE:FBgn0010877
Locus tag
Dmel_CG7129
See related
AllianceGenome:FB:FBgn0010877
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
5822; CG7129; clot 3142; Dmel\CG7129; L(3)05822; l(3)5822; LD12970
Summary
Predicted to be involved in actin filament organization and cell migration. Is expressed in several structures, including anterior endoderm anlage; central brain primordium; dorsal epidermis primordium; ganglia; and mesoderm. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See l(3)05822 in Genome Data Viewer
Location:
91A1-91A2; 3-63 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (18288866..18298879, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (14114588..14124601, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 1A Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Dynein light chain 90F Neighboring gene RNA polymerase I subunit E

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. dtctex-1, the Drosophila melanogaster homolog of a putative murine t-complex distorter encoding a dynein light chain, is required for production of functional sperm. Caggese C, et al. Mol Genet Genomics, 2001 May. PMID 11405626
  2. The Drosophila tctex-1 light chain is dispensable for essential cytoplasmic dynein functions but is required during spermatid differentiation. Li MG, et al. Mol Biol Cell, 2004 Jul. PMID 15090621, Free PMC Article
  3. Bicaudal-C recruits CCR4-NOT deadenylase to target mRNAs and regulates oogenesis, cytoskeletal organization, and its own expression. Chicoine J, et al. Dev Cell, 2007 Nov. PMID 17981137
  4. Genome-wide phenotypic RNAi screen in the Drosophila wing: global parameters. López-Varea A, et al. G3 (Bethesda), 2021 Dec 8. PMID 34599819, Free PMC Article
  5. Misexpression screen delineates novel genes controlling Drosophila lifespan. Paik D, et al. Mech Ageing Dev, 2012 May. PMID 22366109, Free PMC Article

See all (35) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

mobile_element

  • Loc: c18295863-18295675 mobile_element_type = transposon:INE-1{}4876

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
lethal (3) 05822
Names
CG7129-PA
CG7129-PB
CG7129-PC
CG7129-PD
l(3)05822-PA
l(3)05822-PB
l(3)05822-PC
l(3)05822-PD

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    18288866..18298879 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_143794.3 → NP_652051.1  lethal (3) 05822, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_652051.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VE96
    Related
    FBpp0083016
    Conserved Domains (2) summary
    smart00326
    Location:452 → 506
    SH3; Src homology 3 domains
    cl17036
    Location:540 → 591
    SH3; Src Homology 3 domain superfamily

  2. NM_001275774.1 → NP_001262703.1  lethal (3) 05822, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262703.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VE96
    Conserved Domains (2) summary
    smart00326
    Location:452 → 506
    SH3; Src homology 3 domains
    cl17036
    Location:540 → 591
    SH3; Src Homology 3 domain superfamily

  3. NM_001275773.1 → NP_001262702.1  lethal (3) 05822, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262702.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VE96
    Conserved Domains (2) summary
    smart00326
    Location:452 → 506
    SH3; Src homology 3 domains
    cl17036
    Location:540 → 591
    SH3; Src Homology 3 domain superfamily

  4. NM_169802.2 → NP_732322.1  lethal (3) 05822, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_732322.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VE96
    Related
    FBpp0083017
    Conserved Domains (2) summary
    smart00326
    Location:452 → 506
    SH3; Src homology 3 domains
    cl17036
    Location:540 → 591
    SH3; Src Homology 3 domain superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VE96 Q9VE96

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