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dup - double parked

Predicted to enable DNA binding activity and DNA polymerase binding activity. Involved in DNA endoreduplication; DNA replication checkpoint signaling; and glial cell growth. Located in cytoplasm; nucleus; and replication fork. Is expressed in cuboidal/columnar epithelium; female germline stem cell; follicle cell; and optic neuroblast. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 4. Orthologous to human CDT1 (chromatin licensing and DNA replication factor 1). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa