Adf1 Adh transcription factor 1 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Adf1provided by FlyBase
Official Full Name: Adh transcription factor 1provided by FlyBase
Primary source: FLYBASE:FBgn0284249
Locus tag: Dmel_CG15845
See related: AllianceGenome:FB:FBgn0284249
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: Adf; ADF; Adf 1; adf-1; Adf-1; adf1; ADF1; CG15845; Dmel\CG15845; l(2)01349; l(2)04065; l(2)k14805; nal
Summary: Enables DNA-binding transcription activator activity, RNA polymerase II-specific and transcription cis-regulatory region binding activity. Involved in several processes, including positive regulation of transcription by RNA polymerase II; regulation of dendrite development; and synapse assembly. Located in nucleus and polytene chromosome interband. Is expressed in several structures, including adult brain; embryonic/larval midgut primordium; ganglia; gut section; and larval internal muscle motor neurons. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (6662265..6668085)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (2549770..2555590)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IDA Inferred from Direct Assay more info	PubMed
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IDA Inferred from Direct Assay more info	PubMed
enables transcription cis-regulatory region binding	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in larval locomotory behavior	NAS Non-traceable Author Statement more info	PubMed
involved_in learning or memory	NAS Non-traceable Author Statement more info	PubMed
involved_in long-term memory	TAS Traceable Author Statement more info	PubMed
involved_in memory	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in olfactory learning	NAS Non-traceable Author Statement more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of dendrite development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of transcription by RNA polymerase II	IDA Inferred from Direct Assay more info	PubMed
involved_in synapse assembly	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in polytene chromosome interband	IDA Inferred from Direct Assay more info	PubMed
part_of transcription regulator complex	IBA Inferred from Biological aspect of Ancestor more info

Names: Adf1-PA; Adf1-PB; Adf1-PC; Adf1-PE; CG15845-PA; CG15845-PB; CG15845-PC; CG15845-PE; lethal (2) k14805; nalyot; naylot

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