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Spn27A - Serpin 27A

Enables serine-type endopeptidase inhibitor activity. Involved in several processes, including behavioral response to ethanol; defense response to other organism; and negative regulation of protein metabolic process. Located in perivitelline space. Is expressed in several structures, including adult head; embryonic hypopharynx; embryonic large intestine; extraembryonic structure; and gut section. Human ortholog(s) of this gene implicated in intermediate coronary syndrome; neurodegenerative disease (multiple); thrombophilia (multiple); thrombosis; and toxic shock syndrome. Orthologous to several human genes including SERPINA12 (serpin family A member 12); SERPINB1 (serpin family B member 1); and SERPINC1 (serpin family C member 1). [provided by Alliance of Genome Resources, Dec 2024]

Genes similar to Spn27A

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Species Gene Architecture aa