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nompA no mechanoreceptor potential A [ Drosophila melanogaster (fruit fly) ]

Gene ID: 45587, updated on 9-Dec-2024

Summary

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Official Symbol
nompAprovided by FlyBase
Official Full Name
no mechanoreceptor potential Aprovided by FlyBase
Primary source
FLYBASE:FBgn0016047
Locus tag
Dmel_CG13207
See related
AllianceGenome:FB:FBgn0016047
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG13207; Dmel\CG13207; nomp; Nomp-A; NompA; NOMPA; y
Summary
Involved in dendrite morphogenesis; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; and sensory perception of sound. Located in extracellular matrix. Is expressed in several structures, including embryonic head sensory system; embryonic labial sensory complex; mechanosensory sensory organ; sensory nervous system primordium; and sensory organ cell. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See nompA in Genome Data Viewer
Location:
47F1-47F1; 2-64 cM
Exon count:
20
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (11310335..11318676, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (7197840..7206181, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Farnesyl pyrophosphate synthase Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Odorant receptor 47b Neighboring gene shavenoid

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Power gain exhibited by motile mechanosensory neurons in Drosophila ears. Göpfert MC, et al. Proc Natl Acad Sci U S A, 2005 Jan 11. PMID 15623551, Free PMC Article
  2. Functional Interaction Between Drosophila Olfactory Sensory Neurons and Their Support Cells. Prelic S, et al. Front Cell Neurosci, 2021. PMID 35069116, Free PMC Article
  3. Motion generation by Drosophila mechanosensory neurons. Göpfert MC, et al. Proc Natl Acad Sci U S A, 2003 Apr 29. PMID 12642657, Free PMC Article
  4. More whistles and bells for fly hearing. Walker RG. Proc Natl Acad Sci U S A, 2003 May 13. PMID 12732710, Free PMC Article
  5. Myosin VIIA defects, which underlie the Usher 1B syndrome in humans, lead to deafness in Drosophila. Todi SV, et al. Curr Biol, 2005 May 10. PMID 15886106, Free PMC Article

See all (72) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. NompA gene is required for nonsense-mediated mRNA decay pathway.
    Title: Identification and characterization of novel factors that act in the nonsense-mediated mRNA decay pathway in nematodes, flies and mammals.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in anatomical structure morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in dendrite morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in sensory perception of mechanical stimulus IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in sensory perception of sound IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular matrix IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
no mechanoreceptor potential A
Names
CG13207-PA
CG13207-PB
CG13207-PC
CG13207-PD
CG13207-PF
nompA-PA
nompA-PB
nompA-PC
nompA-PD
nompA-PF

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    11310335..11318676 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001299383.1 → NP_001286312.1  no mechanoreceptor potential A, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286312.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4LF37, Q9BMD5
    Conserved Domains (3) summary
    smart00241
    Location:774 → 1013
    ZP; Zona pellucida (ZP) domain
    cd01099
    Location:349 → 424
    PAN_AP_HGF; Subfamily of PAN/APPLE-like domains; present in N-terminal (N) domains of plasminogen/hepatocyte growth factor proteins, and various proteins found in Bilateria, such as leech anti-platelet proteins. PAN/APPLE domains fulfill diverse biological functions ...
    cl42516
    Location:500 → 656
    dnaA; chromosomal replication initiator protein DnaA

  2. NM_165821.4 → NP_725030.2  no mechanoreceptor potential A, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_725030.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1Z8J3, Q9BMD4
    Related
    FBpp0088406
    Conserved Domains (2) summary
    smart00241
    Location:1025 → 1264
    ZP; Zona pellucida (ZP) domain
    cd01099
    Location:349 → 424
    PAN_AP_HGF; Subfamily of PAN/APPLE-like domains; present in N-terminal (N) domains of plasminogen/hepatocyte growth factor proteins, and various proteins found in Bilateria, such as leech anti-platelet proteins. PAN/APPLE domains fulfill diverse biological functions ...

  3. NM_080092.4 → NP_524831.2  no mechanoreceptor potential A, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524831.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1Z8J4, Q9BMD5
    Related
    FBpp0088407

  4. NM_206096.3 → NP_995818.1  no mechanoreceptor potential A, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_995818.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1Z8J3, Q9BMD4
    Conserved Domains (2) summary
    smart00241
    Location:1025 → 1264
    ZP; Zona pellucida (ZP) domain
    cd01099
    Location:349 → 424
    PAN_AP_HGF; Subfamily of PAN/APPLE-like domains; present in N-terminal (N) domains of plasminogen/hepatocyte growth factor proteins, and various proteins found in Bilateria, such as leech anti-platelet proteins. PAN/APPLE domains fulfill diverse biological functions ...

  5. NM_165822.4 → NP_725031.2  no mechanoreceptor potential A, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_725031.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1Z8J4, Q9BMD5
    Related
    FBpp0088405
    Conserved Domains (2) summary
    smart00241
    Location:1025 → 1264
    ZP; Zona pellucida (ZP) domain
    cd01099
    Location:349 → 424
    PAN_AP_HGF; Subfamily of PAN/APPLE-like domains; present in N-terminal (N) domains of plasminogen/hepatocyte growth factor proteins, and various proteins found in Bilateria, such as leech anti-platelet proteins. PAN/APPLE domains fulfill diverse biological functions ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4LF37 A0A0B4LF37
A1Z8J3 A1Z8J3
A1Z8J4 A1Z8J4
Q9BMD4 Q9BMD4
Q9BMD5 Q9BMD5

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