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cradd - CASP2 and RIPK1 domain containing adaptor with death domain

Predicted to enable death domain binding activity and protease binding activity. Predicted to act upstream of or within regulation of apoptotic process and signal transduction. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 34. Orthologous to human CRADD (CASP2 and RIPK1 domain containing adaptor with death domain). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa