tspo translocator protein [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: tspoprovided by ZNC
Official Full Name: translocator proteinprovided by ZNC
Primary source: ZFIN:ZDB-GENE-041010-125
See related: Ensembl:ENSDARG00000026655 AllianceGenome:ZFIN:ZDB-GENE-041010-125
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:103456
Summary: Acts upstream of or within primitive erythrocyte differentiation. Predicted to be located in membrane. Predicted to be active in mitochondrial outer membrane. Is expressed in several structures, including axial blood vessel; blastomere; hematopoietic system; nervous system; and pleuroperitoneal region. Orthologous to several human genes including TSPO (translocator protein). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	6	NC_007117.7 (40578219..40583247, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	6	NC_007117.6 (40580683..40585711, complement)

Chromosome 6 - NC_007117.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

GABA-A receptor and mitochondrial TSPO signaling act in parallel to regulate melanocyte stem cell quiescence in larval zebrafish.
Title: GABA-A receptor and mitochondrial TSPO signaling act in parallel to regulate melanocyte stem cell quiescence in larval zebrafish.
The role of the translocator protein (18 kDa) (TSPO)during development, especially erythroipoiesis, was studied.
Title: Translocator protein (18 kDa) is involved in primitive erythropoiesis in zebrafish.

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within primitive erythrocyte differentiation	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrial outer membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: translocator protein

Names: bzrp1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.