zgc:103759 zgc:103759 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: zgc:103759provided by ZNC
Official Full Name: zgc:103759provided by ZNC
Primary source: ZFIN:ZDB-GENE-041010-100
See related: Ensembl:ENSDARG00000019503 AllianceGenome:ZFIN:ZDB-GENE-041010-100
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary: Predicted to enable phosphodiesterase decapping endonuclease activity and snoRNA binding activity. Predicted to be involved in mRNA catabolic process and sno(s)RNA catabolic process. Predicted to act upstream of or within nucleotide metabolic process. Predicted to be located in nucleolus and nucleoplasm. Predicted to be active in nucleus. Orthologous to human NUDT16 (nudix hydrolase 16) and NUDT16L1 (nudix hydrolase 16 like 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 23

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	23	NC_007134.7 (18702516..18707568, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	23	NC_007134.6 (18776173..18781225, complement)

Chromosome 23 - NC_007134.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity	IEA Inferred from Electronic Annotation more info
enables IDP phosphatase activity	IEA Inferred from Electronic Annotation more info
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables phosphodiesterase decapping endonuclease activity	IBA Inferred from Biological aspect of Ancestor more info
enables snoRNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in mRNA catabolic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within nucleotide metabolic process	IEA Inferred from Electronic Annotation more info
involved_in sno(s)RNA catabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in nucleolus	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: U8 snoRNA-decapping enzyme

NP_001006008.1

EC 3.6.1.62

XP_009295003.1

EC 3.6.1.62

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001006008.2 → NP_001006008.1 U8 snoRNA-decapping enzyme

See identical proteins and their annotated locations for NP_001006008.1

Status: PROVISIONAL

Source sequence(s)

BC083482

UniProtKB/TrEMBL

Q5XJ30

Related

ENSDARP00000003749.5, ENSDART00000016765.7

Conserved Domains (1) summary

cl00447
Location:51 → 86

Nudix_Hydrolase; Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ ...

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007134.7 Reference GRCz11 Primary Assembly

Range

18702516..18707568 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_009296728.4 → XP_009295003.1 U8 snoRNA-decapping enzyme isoform X1

UniProtKB/TrEMBL

A0A8M3B602, E9QD97

Related

ENSDARP00000119874.1, ENSDART00000141205.3

Conserved Domains (1) summary

cl00447
Location:51 → 86

Nudix_Hydrolase; Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ ...