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sdhaf3 succinate dehydrogenase complex assembly factor 3 [ Danio rerio (zebrafish) ]

Gene ID: 449654, updated on 9-Dec-2024

Summary

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Official Symbol
sdhaf3provided by ZNC
Official Full Name
succinate dehydrogenase complex assembly factor 3provided by ZNC
Primary source
ZFIN:ZDB-GENE-041010-94
See related
Ensembl:ENSDARG00000036092 AllianceGenome:ZFIN:ZDB-GENE-041010-94
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
acn9; zgc:92826
Summary
Predicted to be involved in mitochondrial respiratory chain complex II assembly and succinate metabolic process. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrial intermembrane space. Orthologous to human SDHAF3 (succinate dehydrogenase complex assembly factor 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
human mouse all
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Genomic context

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See sdhaf3 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (25526354..25548744)
105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (25942131..25964521)

Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene collagen, type XXVIII, alpha 1a Neighboring gene core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1a Neighboring gene tachykinin precursor 1 Neighboring gene asparagine synthetase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Structure, evolution and expression of collagen XXVIII: Lessons from the zebrafish. Gebauer JM, et al. Matrix Biol, 2016 Jan. PMID 26235539
  2. Zebrafish Collagen Type I: Molecular and Biochemical Characterization of the Major Structural Protein in Bone and Skin. Gistelinck C, et al. Sci Rep, 2016 Feb 15. PMID 26876635, Free PMC Article
  3. A New In Vivo Zebrafish Bioassay Evaluating Liver Steatosis Identifies DDE as a Steatogenic Endocrine Disruptor, Partly through SCD1 Regulation. Le Mentec H, et al. Int J Mol Sci, 2023 Feb 15. PMID 36835354, Free PMC Article
  4. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in mitochondrial respiratory chain complex II assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within mitochondrial respiratory chain complex II assembly IEA
Inferred from Electronic Annotation
more info
  
involved_in mitochondrial respiratory chain complex II assembly IEA
Inferred from Electronic Annotation
more info
  
involved_in succinate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in mitochondrial intermembrane space IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrial matrix IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
succinate dehydrogenase assembly factor 3, mitochondrial
Names
SDH assembly factor 3
protein ACN9 homolog, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005926.2 → NP_001005926.2  succinate dehydrogenase assembly factor 3, mitochondrial precursor

    Status: VALIDATED

    Source sequence(s)
    BX842688, CD595521, EH556844
    UniProtKB/Swiss-Prot
    Q5XIY4
    UniProtKB/TrEMBL
    A0A8M1N249, A3KQK6
    Related
    ENSDARP00000052395.4, ENSDART00000052396.5
    Conserved Domains (1) summary
    pfam13233
    Location:10 → 104
    Complex1_LYR_2; Complex1_LYR-like

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007130.7 Reference GRCz11 Primary Assembly

    Range
    25526354..25548744
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5XIY4.1 GenPept UniProtKB/Swiss-Prot:Q5XIY4

Gene LinkOut

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