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Actn3 alpha actinin 3 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 44964, updated on 28-Oct-2024

Summary

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Official Symbol
Actn3provided by FlyBase
Official Full Name
alpha actinin 3provided by FlyBase
Primary source
FLYBASE:FBgn0015008
Locus tag
Dmel_CG8953
See related
AllianceGenome:FB:FBgn0015008
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
acta-3; actn3; CG8953; dabp; Dmel\CG8953; ORF1
Orthologs
all
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Genomic context

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See Actn3 in Genome Data Viewer
Location:
89E5-89E5; 3-59 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (16975885..16977795, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (12801607..12803517, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Abdominal B Neighboring gene long non-coding RNA:CR46267 Neighboring gene Vacuolar H[+] ATPase M9.7 subunit d Neighboring gene Adenosylhomocysteinase like 2 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mathematical model to predict regions of chromatin attachment to the nuclear matrix. Singh GB, et al. Nucleic Acids Res, 1997 Apr 1. PMID 9060438, Free PMC Article
  2. The bithorax complex of Drosophila melanogaster: Underreplication and morphology in polytene chromosomes. Moshkin YM, et al. Proc Natl Acad Sci U S A, 2001 Jan 16. PMID 11136231, Free PMC Article
  3. Complete sequence of the bithorax complex of Drosophila. Martin CH, et al. Proc Natl Acad Sci U S A, 1995 Aug 29. PMID 7667301, Free PMC Article
  4. Misato underlies visceral myopathy in Drosophila. Min S, et al. Sci Rep, 2017 Dec 18. PMID 29255146, Free PMC Article
  5. Prominent actin fiber arrays in Drosophila tendon cells represent architectural elements different from stress fibers. Alves-Silva J, et al. Mol Biol Cell, 2008 Oct. PMID 18667532, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

General protein information

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Preferred Names
alpha actinin 3
Names
Actn3-PA
CG8953-PA
actinin 3
alpha-actinin-like
alpha-actinin3
open reading frame 1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    16975885..16977795 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_080062.2 → NP_524801.1  alpha actinin 3 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524801.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q4V409, Q9VEQ5
    Related
    FBpp0082822
    Conserved Domains (1) summary
    cd00014
    Location:449 → 546
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q24109 Q24109
Q9VEQ5 Q9VEQ5

Gene LinkOut

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