cox17 cytochrome c oxidase copper chaperone COX17 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: cox17provided by ZNC
Official Full Name: cytochrome c oxidase copper chaperone COX17provided by ZNC
Primary source: ZFIN:ZDB-GENE-040912-91
See related: Ensembl:ENSDARG00000069920 AllianceGenome:ZFIN:ZDB-GENE-040912-91
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:103765; zgc:191605
Summary: Predicted to enable copper chaperone activity. Acts upstream of or within cellular response to copper ion. Predicted to be active in mitochondrial intermembrane space. Is expressed in several structures, including blood; lens; liver; musculature system; and solid lens vesicle. Orthologous to human COX17 (cytochrome c oxidase copper chaperone COX17). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 9

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	9	NC_007120.7 (21235689..21238262, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	9	NC_007120.6 (21424820..21427393, complement)

Chromosome 9 - NC_007120.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables copper chaperone activity	IBA Inferred from Biological aspect of Ancestor more info
enables copper chaperone activity	IEA Inferred from Electronic Annotation more info
enables copper ion binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cellular response to copper ion	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in mitochondrial cytochrome c oxidase assembly	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within response to copper ion	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
is_active_in mitochondrial intermembrane space	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrial intermembrane space	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: cytochrome c oxidase copper chaperone

Names: COX17 cytochrome c oxidase assembly homolog; COX17 cytochrome c oxidase copper chaperone

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.