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gbgt1l3 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3 [ Danio rerio (zebrafish) ]

Gene ID: 447881, updated on 9-Dec-2024

Summary

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Official Symbol
gbgt1l3provided by ZNC
Official Full Name
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3provided by ZNC
Primary source
ZFIN:ZDB-GENE-040912-46
See related
Ensembl:ENSDARG00000035555 AllianceGenome:ZFIN:ZDB-GENE-040912-46
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:101794
Summary
Predicted to enable glycosyltransferase activity. Predicted to be involved in lipid glycosylation. Predicted to act upstream of or within carbohydrate metabolic process. Predicted to be located in membrane. Predicted to be active in Golgi apparatus and vesicle. Human ortholog(s) of this gene implicated in several diseases, including Plasmodium falciparum malaria; graft-versus-host disease; leukemia (multiple); lung disease (multiple); and severe acute respiratory syndrome. Orthologous to several human genes including GBGT1 (globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group)). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See gbgt1l3 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (23849647..23870707, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (23345651..23351647, complement)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4 Neighboring gene glycoprotein, alpha-galactosyltransferase 1 pseudogene Neighboring gene globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 6 Neighboring gene ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Long-term evolution of the CAZY glycosyltransferase 6 (ABO) gene family from fishes to mammals--a birth-and-death evolution model. Turcot-Dubois AL, et al. Glycobiology, 2007 May. PMID 17298992
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables hexosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3
Names
FS-L3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004620.1 → NP_001004620.1  globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3

    See identical proteins and their annotated locations for NP_001004620.1

    Status: PROVISIONAL

    Source sequence(s)
    BC081406
    UniProtKB/TrEMBL
    Q66IC5
    Conserved Domains (1) summary
    cl11394
    Location:75 → 339
    Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    23849647..23870707 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021476095.2 → XP_021331770.1  globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3 isoform X1

    UniProtKB/TrEMBL
    A0A8M9QDS3
    Conserved Domains (1) summary
    cl11394
    Location:80 → 344
    Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

  2. XM_068221155.1 → XP_068077256.1  globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3 isoform X2

    UniProtKB/TrEMBL
    A0A8M9PJY0, A2CED1
    Related
    ENSDARP00000051540.4, ENSDART00000051541.6
Nucleotide Protein
Heading Accession and Version

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