st3gal2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: st3gal2provided by ZNC
Official Full Name: ST3 beta-galactoside alpha-2,3-sialyltransferase 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-050419-181
See related: Ensembl:ENSDARG00000112898 AllianceGenome:ZFIN:ZDB-GENE-050419-181
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: siat5; si:ch211-223o1.7
Summary: Predicted to enable beta-galactoside (CMP) alpha-2,3-sialyltransferase activity. Predicted to be involved in ganglioside biosynthetic process via lactosylceramide; protein glycosylation; and sialylation. Predicted to be located in Golgi cisterna membrane and extracellular region. Predicted to be active in membrane. Is expressed in several structures, including cardiovascular system; fin; head; pleuroperitoneal region; and segmental plate. Orthologous to human ST3GAL2 (ST3 beta-galactoside alpha-2,3-sialyltransferase 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 18

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	18	NC_007129.7 (18588011..18634602)
105	previous assembly	GRCz10 (GCF_000002035.5)	18	NC_007129.6 (18598909..18645536)

Chromosome 18 - NC_007129.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

z33808 (e-PCR), detects polymorphism
- UniSTS:238857

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables beta-galactoside (CMP) alpha-2,3-sialyltransferase activity	IEA Inferred from Electronic Annotation more info
enables beta-galactoside (CMP) alpha-2,3-sialyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables glycosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables sialyltransferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within protein glycosylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
located_in Golgi cisterna membrane	IEA Inferred from Electronic Annotation more info
located_in extracellular region	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2

Names: alpha 2,3-sialyltransferase ST3Gal II; alpha-2,3-sialyltransferase; st3Gal II.2; st3gal2-r1

NP_001004012.1

EC 2.4.3.4

XP_068070859.1

EC 2.4.3.4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.