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Smyd3 SET and MYND domain containing, class 3 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 44554, updated on 9-Dec-2024

Summary

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Official Symbol
Smyd3provided by FlyBase
Official Full Name
SET and MYND domain containing, class 3provided by FlyBase
Primary source
FLYBASE:FBgn0011566
Locus tag
Dmel_CG13761
See related
AllianceGenome:FB:FBgn0011566
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Bzd; CG13761; Dmel\CG13761; EG:BACR7C10.4
Summary
Predicted to enable protein-lysine N-methyltransferase activity. Predicted to be active in nucleus. Orthologous to several human genes including SMYD3 (SET and MYND domain containing 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See Smyd3 in Genome Data Viewer
Location:
3A7-3A7; 1-1 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (2606680..2608876, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (2500713..2502909, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene egghead Neighboring gene Kinesin-like protein at 3A Neighboring gene Zeste-white 10 Neighboring gene eukaryotic translation initiation factor 3 subunit g1 Neighboring gene Tetraspanin 3A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Evolutionary History of the Smyd Gene Family in Metazoans: A Framework to Identify the Orthologs of Human Smyd Genes in Drosophila and Other Animal Species. Calpena E, et al. PLoS One, 2015. PMID 26230726, Free PMC Article
  2. DEAF-1 function is essential for the early embryonic development of Drosophila. Veraksa A, et al. Genesis, 2002 Jun. PMID 12112874
  3. Reagent and Data Resources for Investigation of RNA Binding Protein Functions in Drosophila melanogaster Cultured Cells. Mohr SE, et al. G3 (Bethesda), 2015 Jul 21. PMID 26199285, Free PMC Article
  4. TRF4, the novel TBP-related protein of Drosophila melanogaster, is concentrated at the endoplasmic reticulum and copurifies with proteins participating in the processes associated with endoplasmic reticulum. Kurshakova MM, et al. J Cell Biochem, 2019 May. PMID 30426565
  5. Transcription profiling in Drosophila eyes that overexpress the human glaucoma-associated trabecular meshwork-inducible glucocorticoid response protein/myocilin (TIGR/MYOC). Borrás T, et al. Genetics, 2003 Feb. PMID 12618402, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables protein-lysine N-methyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
SET and MYND domain containing, class 3
Names
CG13761-PB
Smyd3-PB
buzidau

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    2606680..2608876 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_080029.4 → NP_524768.2  SET and MYND domain containing, class 3 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524768.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MRV6, Q9NF43, Q9W4X8
    Related
    FBpp0070431
    Conserved Domains (2) summary
    pfam01753
    Location:60 → 97
    zf-MYND; MYND finger
    pfam13424
    Location:377 → 440
    TPR_12; Tetratricopeptide repeat
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8MRV6 Q8MRV6
Q9W4X8 Q9W4X8

Gene LinkOut

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