cdc26 cell division cycle 26 homolog [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: cdc26provided by ZNC
Official Full Name: cell division cycle 26 homologprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040822-18
See related: Ensembl:ENSDARG00000077815 AllianceGenome:ZFIN:ZDB-GENE-040822-18
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: apc12; zgc:100965
Summary: Acts upstream of or within mitotic cell cycle and regulation of mitotic cell cycle. Predicted to be located in nucleus. Predicted to be part of anaphase-promoting complex. Is expressed in digestive system; head; and heart. Orthologous to human CDC26 (cell division cycle 26). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	5	NC_007116.7 (57359539..57372471, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	5	NC_007116.6 (56689322..56702496, complement)

Chromosome 5 - NC_007116.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fe12c05.y1 (e-PCR)
- UniSTS:196101

fd05c02.x1 (e-PCR)
- UniSTS:194951

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within anaphase-promoting complex-dependent catabolic process	IEA Inferred from Electronic Annotation more info
involved_in anaphase-promoting complex-dependent catabolic process	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within cell division	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within mitotic cell cycle	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein K11-linked ubiquitination	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein K11-linked ubiquitination	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein K48-linked ubiquitination	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein branched polyubiquitination	ISS Inferred from Sequence or Structural Similarity more info
involved_in regulation of mitotic cell cycle	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within regulation of mitotic cell cycle	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of anaphase-promoting complex	IBA Inferred from Biological aspect of Ancestor more info
part_of anaphase-promoting complex	IEA Inferred from Electronic Annotation more info
part_of anaphase-promoting complex	ISS Inferred from Sequence or Structural Similarity more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: anaphase-promoting complex subunit CDC26

Names: cell division cycle protein 26 homolog; gog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001004005.2 → NP_001004005.1 anaphase-promoting complex subunit CDC26

See identical proteins and their annotated locations for NP_001004005.1

Status: VALIDATED

Source sequence(s)

EH488188, EH539725

UniProtKB/Swiss-Prot

A2CES9, Q68EK9

Related

ENSDARP00000100739.2, ENSDART00000112793.4

Conserved Domains (1) summary

pfam10471
Location:1 → 56

ANAPC_CDC26; Anaphase-promoting complex APC subunit CDC26

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007116.7 Reference GRCz11 Primary Assembly

Range

57359539..57372471 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_068221152.1 → XP_068077253.1 anaphase-promoting complex subunit CDC26 isoform X1

UniProtKB/Swiss-Prot

A2CES9, Q68EK9
XM_068221151.1 → XP_068077252.1 anaphase-promoting complex subunit CDC26 isoform X1

UniProtKB/Swiss-Prot

A2CES9, Q68EK9